{"id":1020,"date":"2021-09-24T10:49:43","date_gmt":"2021-09-24T17:49:43","guid":{"rendered":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/?page_id=1020"},"modified":"2021-12-23T23:36:43","modified_gmt":"2021-12-24T07:36:43","slug":"f-i-a-b-s","status":"publish","type":"page","link":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/f-i-a-b-s\/","title":{"rendered":"Computational Neuroscience"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text css=&#8221;.vc_custom_1632948035529{margin-right: 1px !important;margin-bottom: 2px !important;margin-left: 1px !important;border-right-width: 2px !important;border-left-width: 2px !important;padding-top: 2px !important;padding-right: 20px !important;padding-bottom: 2px !important;padding-left: 20px !important;background-color: #ffffff !important;border-left-color: #dd3333 !important;border-left-style: outset !important;border-right-color: #dd3333 !important;border-right-style: outset !important;border-radius: 20px !important;}&#8221;]<\/p>\n<p style=\"text-align: justify\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/03\/DetailedModel.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-885 size-medium\" src=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/03\/DetailedModel-300x225.png\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/03\/DetailedModel-300x225.png 300w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/03\/DetailedModel-1024x768.png 1024w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/03\/DetailedModel-768x576.png 768w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/03\/DetailedModel.png 1500w\" sizes=\"auto, (max-width: 300px) 85vw, 300px\" \/><\/a><\/p>\n<p style=\"font-size: 20px;font-family: Montserrat;color: black;text-align: justify\">Our ongoing research is developing widely disseminable: <strong>1)<\/strong> functional interactomes across brain scales and, <strong>2)<\/strong> <em>in silico<\/em> co-cultures of diverse cell types (e.g., neurons, astrocytes and microglia) which will permit studying the complex crosstalk between neural excitability, neuroinflammation and neuroendocrine subsystems in health and disease. The models which we construct and study feature a great degree of biological realism and offer molecular level insights into the dynamics of whole brain function. This project involves solid multidisciplinary training in Life and Physical Sciences as well as Bioengineering.<\/p>\n<p style=\"font-size: 20px;font-family: Montserrat;color: black;text-align: justify\">Some of our recent reports include (For a full list of our published work, click <a href=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/publications\/\" rel=\"noopener\">here<\/a>):<\/p>\n<p style=\"font-size: 20px;font-family: Montserrat;color: black;text-align: justify\"><a style=\"font-family: Merriweather, Georgia, serif;font-size: 16px;font-weight: 400\" href=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/10\/PolitPLOSPaper.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1168 size-medium alignleft\" src=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/10\/PolitPLOSPaper-286x300.png\" alt=\"\" width=\"286\" height=\"300\" srcset=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/10\/PolitPLOSPaper-286x300.png 286w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2021\/10\/PolitPLOSPaper.png 559w\" sizes=\"auto, (max-width: 286px) 85vw, 286px\" \/><\/a><\/p>\n<p style=\"font-size: 20px;font-family: Montserrat;color: black;text-align: justify\">A Multicellular Network to Study Intrinsic Rhythms and Neural Control of Gastric Peristalsis (2021) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34871315\/\">PMID: 34871315<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"font-size: 20px;font-family: Montserrat;color: black\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-489\" src=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/06\/Fig9-Summary-300x169.jpg\" alt=\"\" width=\"400\" height=\"226\" srcset=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/06\/Fig9-Summary-300x169.jpg 300w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/06\/Fig9-Summary-768x434.jpg 768w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/06\/Fig9-Summary-1024x578.jpg 1024w\" sizes=\"auto, (max-width: 400px) 85vw, 400px\" \/>A New Role for Voltage-Gated Sodium Channels in Noise Modulation (2019) <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31226124\" target=\"_blank\" rel=\"noopener\">PMID: 31226124<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-692 size-medium alignleft\" style=\"color: #007acc\" src=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/12\/denizot-300x250.png\" alt=\"\" width=\"300\" height=\"250\" srcset=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/12\/denizot-300x250.png 300w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/12\/denizot-768x640.png 768w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/12\/denizot-1024x853.png 1024w, https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-content\/uploads\/sites\/38\/2019\/12\/denizot.png 1333w\" sizes=\"auto, (max-width: 300px) 85vw, 300px\" \/><\/p>\n<p style=\"font-size: 20px;font-family: Montserrat;color: black;text-align: left\">A book chapter on computational models of astrocyte Ca2+ signals in the Encyclopedia of Computational Neuroscience (2019) <a href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007%2F978-1-4614-7320-6_100693-1.pdf\" target=\"_blank\" rel=\"noopener\">Link<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<p>&nbsp;<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text css=&#8221;.vc_custom_1632948035529{margin-right: 1px !important;margin-bottom: 2px !important;margin-left: 1px !important;border-right-width: 2px !important;border-left-width: 2px !important;padding-top: 2px !important;padding-right: 20px !important;padding-bottom: 2px !important;padding-left: 20px !important;background-color: #ffffff !important;border-left-color: #dd3333 !important;border-left-style: outset !important;border-right-color: #dd3333 !important;border-right-style: outset !important;border-radius: 20px !important;}&#8221;] Our ongoing research is developing widely disseminable: 1) functional interactomes across brain scales and, 2) in silico co-cultures of diverse cell types (e.g., &hellip; <a href=\"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/f-i-a-b-s\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Computational Neuroscience&#8221;<\/span><\/a><\/p>\n","protected":false},"author":57,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1020","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/pages\/1020","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/users\/57"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/comments?post=1020"}],"version-history":[{"count":17,"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/pages\/1020\/revisions"}],"predecessor-version":[{"id":1241,"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/pages\/1020\/revisions\/1241"}],"wp:attachment":[{"href":"https:\/\/sites.lifesci.ucla.edu\/ibp-venugopal\/wp-json\/wp\/v2\/media?parent=1020"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}