Devin Gibbs

Devin studies the development of humanized skeletal muscle models for the evaluation of gene editing and stem cell approaches for Duchenne Muscular Dystrophy.

Publications:

Effect of serotonin modulation on dystrophin-deficient Zebrafish – Spinazzola, J. M., Lambert, M. R., Gibbs, D.E., Conner, J. R., Krikorian, G. L.. Pareek, P., Rago, C., & Kunkel, L. M. (2020). Biology Open. (in press)

The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice – Hightower, R. M., Reid, A. L., Gibbs, D. E., Wang, Y., Widrick, J. J., Kunkel, L. M., Kastenschmidt, J. M., Villalta, S. A., van Groen, T., Chang, H., Gornisiewicz, S., Landesman, Y., Tamir, S., & Alexander, M. S. (2020). Molecular therapy : the journal of the American Society of Gene Therapy, 28(1), 189–201. https://doi.org/10.1016/j.ymthe.2019.08.016

Transgenic zebrafish model of DUX4 misexpression reveals a developmental role in FSHD pathogenesis – Pakula, A., Lek, A., Widrick, J., Mitsuhashi, H., Bugda Gwilt, K. M., Gupta, V. A., Rahimov, F., Criscione, J., Zhang, Y., Gibbs, D., Murphy, Q., Manglik, A., Mead, L., & Kunkel, L. (2019). Human molecular genetics, 28(2), 320–331. https://doi.org/10.1093/hmg/ddy348

A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies – Serafini P.R., Feyder M.J., Hightower R.M., Garcia-Perez, Vieira N.M,. Lek A., Gibbs D.E., Moukha-Chafiq O., Augelli-Szafran C.E., Kawahara G., Widrick J.J., Kunkel L.M., Alexander M.S.. (2018). A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies. JCI Insight. 20;3(18).