{"id":18,"date":"2017-04-19T12:37:41","date_gmt":"2017-04-19T19:37:41","guid":{"rendered":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/?page_id=18"},"modified":"2019-06-13T15:30:48","modified_gmt":"2019-06-13T22:30:48","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/publications\/","title":{"rendered":"PUBLICATIONS"},"content":{"rendered":"<div class='flex_column_table av-5pwo2-3f35ee9ed92475220a9ae0ba0b6f4d07 sc-av_three_fourth av-equal-height-column-flextable'>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5pwo2-3f35ee9ed92475220a9ae0ba0b6f4d07\">\n.flex_column.av-5pwo2-3f35ee9ed92475220a9ae0ba0b6f4d07{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-5pwo2-3f35ee9ed92475220a9ae0ba0b6f4d07 av_three_fourth  avia-builder-el-0  el_before_av_one_fourth  avia-builder-el-first  first no_margin flex_column_table_cell av-equal-height-column av-align-top av-zero-column-padding  '     ><div  class='avia-slideshow av-542ha-fc1d6679349e5e6dab1b723fe0626464 avia-slideshow-no scaling av_slideshow avia-fade-slider  avia-builder-el-1  avia-builder-el-no-sibling  av-slideshow-ui av-control-hidden av-no-slider-navigation av-hide-nav-arrows av-slideshow-manual av-loop-once av-loop-manual-endless av-default-height-applied avia-slideshow-1' data-slideshow-options=\"{&quot;animation&quot;:&quot;fade&quot;,&quot;autoplay&quot;:false,&quot;loop_autoplay&quot;:&quot;once&quot;,&quot;interval&quot;:4,&quot;loop_manual&quot;:&quot;manual-endless&quot;,&quot;autoplay_stopper&quot;:false,&quot;noNavigation&quot;:true,&quot;bg_slider&quot;:false,&quot;keep_padding&quot;:false,&quot;hoverpause&quot;:false,&quot;show_slide_delay&quot;:0}\"  itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><ul class='avia-slideshow-inner ' style='padding-bottom: 30.714285714286%;'><li  class='avia-slideshow-slide av-542ha-fc1d6679349e5e6dab1b723fe0626464__0  av-single-slide slide-1 slide-odd'><div data-rel='slideshow-1' class='avia-slide-wrap '   ><img fetchpriority=\"high\" class=\"wp-image-200 avia-img-lazy-loading-not-200\"  src='https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/pubsBanner.jpg' width='840' height='258' title='pubsBanner' alt=''  itemprop=\"thumbnailUrl\"   \/><\/div><\/li><\/ul><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-45c8y-25810a14b3c2b1f20939e78bd74cbd21\">\n.flex_column.av-45c8y-25810a14b3c2b1f20939e78bd74cbd21{\nborder-width:10px;\nborder-color:#ffffff;\nborder-style:solid;\nborder-radius:0px 0px 0px 0px;\npadding:0 0 0 10px;\nbackground-color:#cccccc;\n}\n<\/style>\n<div  class='flex_column av-45c8y-25810a14b3c2b1f20939e78bd74cbd21 av_one_fourth  avia-builder-el-2  el_after_av_three_fourth  el_before_av_one_full  no_margin flex_column_table_cell av-equal-height-column av-align-top  '     ><div  class='avia-builder-widget-area clearfix  avia-builder-el-3  avia-builder-el-no-sibling '><div id=\"nav_menu-2\" class=\"widget clearfix widget_nav_menu\"><div class=\"menu-mainsideheadmenu-container\"><ul id=\"menu-mainsideheadmenu\" class=\"menu\"><li id=\"menu-item-47\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-home menu-item-47\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/\">HOME<\/a><\/li>\n<li id=\"menu-item-46\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-46\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/research\/\">RESEARCH<\/a><\/li>\n<li id=\"menu-item-45\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-45\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/publications\/\">PUBLICATIONS<\/a><\/li>\n<li id=\"menu-item-44\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-44\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/people\/\">PEOPLE<\/a><\/li>\n<li id=\"menu-item-43\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-43\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/protocols-reagents\/\">PROTOCOLS &#038; REAGENTS<\/a><\/li>\n<li id=\"menu-item-42\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-42\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/news-events\/\">NEWS &#038; EVENTS<\/a><\/li>\n<li id=\"menu-item-41\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-41\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/join-the-lab\/\">JOIN THE LAB<\/a><\/li>\n<li id=\"menu-item-40\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-40\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/contact-us\/\">CONTACT US<\/a><\/li>\n<li id=\"menu-item-381\" class=\"menu-item menu-item-type-custom menu-item-object-custom menu-item-381\"><a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-vbtg\/\" title=\"vbtg\">VASCULAR BIOLOGY TRAINING GRANT<\/a><\/li>\n<\/ul><\/div><\/div><\/div><\/div><\/div><!--close column table wrapper. Autoclose: 1 -->\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2x5fi-6273b8e8d6e3f04c564dd4daf10fe45f\">\n.flex_column.av-2x5fi-6273b8e8d6e3f04c564dd4daf10fe45f{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-2x5fi-6273b8e8d6e3f04c564dd4daf10fe45f av_one_full  avia-builder-el-4  el_after_av_one_fourth  el_before_av_one_full  first flex_column_div av-zero-column-padding  column-top-margin'     ><section  class='av_textblock_section av-1uwyq-8bbd779430b35994b319082905b37147 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><div class=\"col-sm-12 col-md-8\">\n<article id=\"post-253\" class=\"post-253 page type-page status-publish has-post-thumbnail hentry\">\n<header>\n<h1 class=\"page-title\">Publications<\/h1>\n<\/header>\n<div class=\"entry-content\">\n<p><a href=\"#2019\">2019<\/a> | <a href=\"#2018\">2018<\/a> | <a href=\"#2017\">2017<\/a> | <a href=\"#2016\">2016<\/a> | <a href=\"#2015\">2015<\/a> | <a href=\"#2014\">2014<\/a> | <a href=\"#2013\">2013<\/a> | <a href=\"#2012\">2012<\/a> | <a href=\"#2011\">2011<\/a> | <a href=\"#2010\">2010<\/a> | <a href=\"#2009\">2009<\/a> | <a href=\"#2008\">2008<\/a> | <a href=\"#2007\">2007<\/a> | <a href=\"#2006\">2006<\/a> | <a href=\"#2005\">2005 <\/a>| <a href=\"#2004\">2004<\/a> | <a href=\"#2003\">2003<\/a> | <a href=\"#2002\">2002 <\/a>| <a href=\"#2001\">2001<\/a> | <a href=\"#2000\">2000<\/a> | <a href=\"#1990s\">1990s<\/a> |<a href=\"#1980s\"> 1980s <\/a>|<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2019\"><\/a><\/p>\n<h4><a id=\"2019\"><\/a>2019<\/h4>\n<p><a class=\"mwm-aal-item\" name=\"2018\"><\/a><br \/>\nRomay, M.C., Toro, C., <strong>Iruela-Arispe, M.L<\/strong>. 2019. <a href=\"https:\/\/doi.org\/10.1097\/MOH.0000000000000502\" target=\"_blank\" rel=\"noopener noreferrer\">Emerging molecular mechanisms of vascular dementia<\/a>. Curr Opin Hematol. 26(3):199-206. PMID: 30883434<\/p>\n<p><strong>Iruela-Arispe, ML.<\/strong> 2019. <a href=\"https:\/\/doi.org\/10.1097\/MOH.0000000000000504\" target=\"_blank\" rel=\"noopener noreferrer\">A focus on vascular malformations.<\/a> Curr Opin Hematol. 26(3): 152-153. PMID: 30870249.<\/p>\n<p>Keklikoglou, I., CIanciaruso, C., Guc, E., Squadrito, M.L., Spring, L.M., Tazzyman, S., Lambien, L., Poissonnier, A., Ferraro, G.B., Baer, C., Cassara, A., Guichard, A., <strong>Iruela-Arispe, M.L.<\/strong>, Lewis, C.E., Coussens, L.M., Bardia, A., Jain, R.K., Pollard, J.W., De Palma, M. 2018. <a href=\"https:\/\/www.doi.org\/10.1038\/s41556-018-0256-3\" target=\"_blank\" rel=\"noopener noreferrer\">Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models<\/a>. Nature Cell Biol. 21(2). PMID: 30598531 DOI: 10.1038\/s41556-018-0256-3.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2018\"><\/a><\/p>\n<h4><a id=\"2018\"><\/a>2018<\/h4>\n<p><strong>Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"http:\/\/doi.org\/10.1084\/jem.20181537\" target=\"_blank\" rel=\"noopener noreferrer\">Pumping blood with self-reliance and cooperation<\/a>. JEM. 215(10):2480-2482. PMID: 30228158 PMCID: PMC6170172<\/p>\n<p><strong>Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"https:\/\/www.nature.com\/articles\/d41586-018-06199-2\" target=\"_blank\" rel=\"noopener noreferrer\">A dual origin for blood vessels<\/a>. Nature. 562(7726):195-197. PMID: 30291309<\/p>\n<p>McDonald, A.I., Shirali, A.S., Arag\u00f3n, R., Ma, F., Hernandez, G., Vaughn, D.A., Mack, J.J., Lim, T.Y., Sunshine, H., Zhao, P., Kalinichenko,\u00a0 V., Pelegrini, M., Ardehali, R., and <strong>Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"https:\/\/doi.org\/10.1016\/j.stem.2018.07.011\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial Regeneration of Large Vessels is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities<\/a>. Cell Stem Stell. 23(2):210-225. PMID: 30075129 PMCID: PMC6178982 [Available on 2019-08-02]<\/p>\n<p>Archer, B., Ueberrueck, T., Mack, J.J., Yousef, K., Jarenwattananon, N.N., Rall, D., Wypysek, D., Wiese, M., Bluemich, B., Wessling, M., <strong>Iruela-Arispe, M.L.<\/strong>, Bouchard, L. 2018. <a href=\"https:\/\/ieeexplore.ieee.org\/stamp\/stamp.jsp?tp=&amp;arnumber=8412441\" target=\"_blank\" rel=\"noopener noreferrer\">Non-Invasive Quantification of Cell Density in 3D Gels by MRI<\/a>. IEEE Trans Biomed Eng. 66(3):821-830. PMID: 30028689<\/p>\n<p>Jelinek, D., Flores, A., Uebelhoer, M., Pasque, V., Plath, K., <strong>Iruela-Arispe, M.L.<\/strong>, Christofk, H.R., Lowry, W.E., Coller, H.A. 2018. <a href=\"https:\/\/www.jove.com\/video\/57760\/mapping-metabolism-monitoring-lactate-dehydrogenase-activity-directly\" target=\"_blank\" rel=\"noopener noreferrer\">Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue<\/a>. J Vis Exp. (136): e58860. PMID: 29985359 PMCID: PMC6101961 [Available on 2019-06-21] DOI: 10.3791\/57760<\/p>\n<p>Chattopadhyay, A., Yang, X., Mukherjee, P., Sulaiman, D., Fogelman, H.R., Grijalva, V., Dubinnet, S., Wasler, T.C., Paul, M.K., Salehi-Rad, R., Mack, J.J.,<strong> Iruela-Arispe, M.L.<\/strong>, Navab, M., Fogelman, A.M., Reddy, S.T. 2018. <a href=\"https:\/\/www.nature.com\/articles\/s41598-018-26755-0.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer<\/a>. Sci Rep. 8(1): 9032. PMID: 29899427 PMCID: PMC5998131<\/p>\n<p>Hilfenhaus, G., Nguyen, D., Freshman, J., Prajapati, D., Ma, F., Song, D., Ziyad, S., Cuadrado, M., Pellegrini, M., Bustelo, X.R.,<strong> Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"http:\/\/jcb.rupress.org\/content\/early\/2018\/05\/31\/jcb.201706041\" target=\"_blank\" rel=\"noopener noreferrer\">VAV3-induced Cytoskeletal Dynamics Contribute to Heterotypic Properties of Endothelial Barriers<\/a>. J Cell Biol. 217(8):2813-2830. PMID: 29858212 PMCID: PMC6080943<\/p>\n<p>Nowak-Sliwinska, P., Alitalo, K., Allen, A., Anisimov, A., Aplin, A.C., Auerbach, R., Augustin, A.G., Bates, D.O., van Beijnum, J.T., Bender, R.H.,F., Bergers,G., Bikfalvi, A., Bischoff, J., B\u00f6ck, B.C., Brooks, P.C., Bussolino, F., Cakir, B., Carmeliet, P., Castranova, D., Cimpean, A.M., Cleaver, O., Coukos, G., Davis, G.E., De Palma, M., Dimberg, A., Dings, R.P.M., Djonov, V., Dudley, A.C., Dufton, N.P., Fendt, S.M., Ferrara, N., Fruttiger, M., Fukumura, D., Ghesui\u00e8re, B., Gong, Y., Griffin, R.J., Harris, A.L., Hughes, C.C.W., Hultgren, N.W., <strong>Iruela-Arispe, M.L.,<\/strong> Irving, M., Jain, R.K., Kalluri, R., Kalucka, J., Kerbel, R.S., Kitajewski, J., Klaassen, I., Kleinmann, H.K., Koolwijk, P., Kuczynski, E., Kwak, B.R., K. Marien, J. M. Melero-Martin, L. L. Munn, R. F. Nicosia, A. Noel, J. Nurro, A.-K. Olsson, T. V. Petrova, Pietras, K., Pili, R., Pollard, J.W., Post, M.J., Quax, P.H.A., Rabinovich, G.A., Raica, M., Randi, A.M., Ribatti, D., Ruegg, C., Schlingemann, R.O., Schulte-Merker, S., Smith, L.E.H., Song, J.W., Stacker, S.A., Stalin, J., Stratman, A.N., Van de Velde, M., van Hinsbergh, V.W.M., Vermeulen, P.B., Waltenberger, J., Weinstein, B.M., Xin, H., Yetkin-Arik, B., Yla-Herttuala, S., Yoder, M.C., Griffioen, A.W. 2018. <a href=\"https:\/\/doi.org\/10.1007\/s10456-018-9613-x\" target=\"_blank\" rel=\"noopener noreferrer\">Consensus guidelines for the use and interpretation of angiogenesis assays<\/a>. Angiogenesis. 21(3):425-532.\u00a0PMID: 29766399 PMCID: PMC6237663 [Available on 2019-08-01]<\/p>\n<p>Mack, J.J., <strong>Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"https:\/\/insights.ovid.com\/pubmed?pmid=29547401\" target=\"_blank\" rel=\"noopener noreferrer\">NOTCH regulation of the endothelial cell phenotype<\/a>. Curr Opin Hematol. PMID: 29547401<\/p>\n<p>Freitas, V.M., Hilfenhaus, G., <strong>Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1534580718301928?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Metastasis of Circulating Tumor Cells: Speed Matters<\/a>. Dev Cell. 45(1): 3-5.<\/p>\n<p>Shirali, A.S., Romay, M.C., McDonald, A.I., Su, T., Steel, M.E., <strong>Iruela-Arispe, M.L.<\/strong> 2018. <a href=\"https:\/\/www.nature.com\/articles\/s41598-018-23653-3\" target=\"_blank\" rel=\"noopener noreferrer\">A\u00a0multi-step transcriptional cascade underlies vascular regeneration in vivo<\/a>. Scientific Reports. 8(1):5430.<\/p>\n<p>Li, L. Zheng, Q. Bhutkar,\u00a0A., Galv\u00e1n, J., Karamitopoulou, E., Necsulea, A., Noordermeer, D., Piersigilli, A., Peng, M., Perren, A., Ziobec, I., Robinson, H., <strong>Iruela-Arispe, M.L.<\/strong>, Hanahan, D. 2018. <a href=\"http:\/\/www.cell.com\/cancer-cell\/fulltext\/S1535-6108(18)30064-3\" target=\"_blank\" rel=\"noopener noreferrer\">GKAP acts as a genetic modulator of NMDAR signaling to govern invasive tumor growth<\/a>. Cancer Cell. 33(4)736-751.e5.<\/p>\n<p>Sereti, K.I., Nguyen, N.B., Kamran, P., Zhao, P., Ranjbarvaziri, S., Park, S., Sabri, S., Engel, J.L., Sung, K., Kulkarni, R.P., Ding, Y., Hsiai, T.K., Plath, K., Ernst, J., Sahoo, D., Mikkola, H.K.A., <strong>Iruela-Arispe, M.L.<\/strong>, Ardehali, R. 2018. <a href=\"https:\/\/www.nature.com\/articles\/s41467-018-02891-z.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Analysis of cardiomyocyte clonal expansion during mouse heart development and injury<\/a>. Nat Commun. 9(1): 754. PMCID: PMC5821855<\/p>\n<p>Ziyad, S., Riordan, J.D., Cavanaugh, A.C., Su, T., Hernandez, G.E., Hilfenhaus, G., Morselli, M., Huyn, K., Wang, K., Chen, J.N., Dupuy, A.J., <strong>Iruela-Arispe, M.L<\/strong>. 2018. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5828030\/pdf\/nihms941209.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">A forward genetic screen targeting the endothelium reveals a regulatory role for the lipid kinase Pi4Ka in myelo- and erythropoiesis<\/a>. Cell Reports. 22(5): 1211-1224. PMCID: PMC5828030<\/p>\n<p>Duran, I., Tenney, J., Warren, C.M., Sarukhanov, A., Csukasi, F., Skalansky, M., <strong>Iruela-Arispe, M.L.<\/strong>, Krakow, D. 2018. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1002\/ajmg.a.38600\" target=\"_blank\" rel=\"noopener noreferrer\">NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot<\/a>. Am J Med Genet A. 176(3): 649-656.<\/p>\n<p><strong>Iruela-Arispe, L.M.<\/strong> 2018. <a href=\"https:\/\/link.springer.com\/referencework\/10.1007%2F978-3-319-67199-4\" target=\"_blank\" rel=\"noopener noreferrer\">VEGF<\/a>. Chapter in: Encyclopedia of Signaling Molecules, 2nd Edition. Springer. Sangdun Choi, Editor-in-Chief. Pp 5915-5920.<\/p>\n<p>Mundi, S., Massaro, M., Scoditti, E., Carluccio, M.A., van Hunsberg, V.W.M., <strong>Iruela-Arispe, M.L.<\/strong>, De Caterina, R. 2018. <a href=\"https:\/\/doi.org\/10.1093\/cvr\/cvx226\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial permeability, LDL deposition, and cardiovascular risk factors-a review<\/a>. Cardiovasc. Res. 114(1): 35-52.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2017\"><\/a><\/p>\n<h4><a id=\"2017\"><\/a>2017<\/h4>\n<p>Mack, J.J., Mosqueiro, T.S., Archer, B.J., Jones, W.M., Sunshine, H., Faas, G.C., Briot, A., Arag\u00f3n, R., Su, Y.T., Romay, M.C., McDonald, A.I., Kuo, C., Lizama, C.O., Lane, T.F., Zovein, A.C., Fang, Y., Tarling, E.J., de Aguiar Vallim, T.Q., Navab, M., Fogelman, A.M., Bouchard, L.S.,<strong> Iruela-Arispe., M.L. <\/strong>2017. <a href=\"https:\/\/www.nature.com\/articles\/s41467-017-01741-8.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">NOTCH1 is a mechanosensor in adult arteries<\/a>. Nature Communications. 8(1), 1620.<\/p>\n<p>Sunshine, H., <strong>Iruela-Arispe, M.L.<\/strong> 2017. <a href=\"https:\/\/journals.lww.com\/co-lipidology\/Abstract\/2017\/10000\/Membrane_lipids_and_cell_signaling.5.aspx\" target=\"_blank\" rel=\"noopener noreferrer\">Membrane lipids and cell signaling<\/a>. Curr Opin Lipidol. 28(5): 408-413.<\/p>\n<p>Toullec, A., Valerie, B., Rannou, E., Tarlet, G., Guipaud, O., Robine, S., <strong>Iruela-Arispe, L.M.<\/strong>, Francois, A., Milliat, F. 2017. <a href=\"https:\/\/ac.els-cdn.com\/S2352345X17301315\/1-s2.0-S2352345X17301315-main.pdf?_tid=8cca1dae-d6bd-11e7-8028-00000aacb35d&amp;acdnat=1512149706_dfade44f1ee921627564741ad6a14acf\" target=\"_blank\" rel=\"noopener noreferrer\">HIF-1\u03b1 deletion in the endothelium, but not in the epithelium, protects from radiation-induced enteritis<\/a>. Cell Mol Gastroenterol Hepatol. 5(1): 15-30.<\/p>\n<p>Mukherjee, P., Hough, G., Chattopadhyay, A., Navab, M., Fogelman, H. R., Meriwether, D., Williams,K., Bensinger,S., Moller, T., Faull, K.F., Lusis, A., <strong>Iruela-Arispe, M.L.<\/strong>, Bostrom, K., Tontonoz, P., Reddy, S., Fogelman, A. 2017. <a href=\"http:\/\/www.jlr.org\/content\/early\/2017\/06\/13\/jlr.M076554.full.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Transgenic Tomatoes Expressing the 6F Peptide and Ezetimibe Prevent Diet-induced Increases of Interferon-\u03b2 and Cholesterol 25-hydroxylase in Jejunum.\u00a0Journal of Lipid Research<\/a>. J Lipid Res. 58(7):e076554.<\/p>\n<p>Rose, B.A., Yokota, T., Chintalgattu, V., Ren, S., <strong>Iruela-Arispe, M.L.<\/strong>, Khakoo, A.Y., Wang, Y. 2017. <a href=\"http:\/\/www.jbc.org\/content\/292\/31\/12787\" target=\"_blank\" rel=\"noopener noreferrer\">Cardiac Myocyte p38\u03b1 Kinase Regulates Angiogenesis via Myocyte-Endothelial Cell Cross-talk During Stress-Induced Remodeling in Heart. Journal of Biological Chemistry<\/a>. J Biol Chem. 292(31): 12787-12800.<\/p>\n<p>Mintet, E., Lavigne, J., Paget, V., Tarlet, G., Buard, V., Guipaud, O., Sabourin, J.C., <strong>Iruela-Arispe, M.L.<\/strong>, Milliat F, Francois A. 2017. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5503994\/pdf\/41598_2017_Article_5389.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice<\/a>. Scientific Reports. 7(1)4933.<\/p>\n<p>Jumabay, M., Zhumabai, J., Mansurov, N., Niklason, K.C., Guihard, P.J., Fogelman, A.M., <strong>Iruela-Arispe, M.L.<\/strong>, Yao, Y., Saparov, A., Bostrom, K.I. 2017. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcp.25983\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Combined effects of bone morphogenetic protein 10 and crossveinless-2 on cardiomyocyte differentiation in mouse adipocyte-derived stem cells.<\/a> J Cell Physiol. 233(3):1812-1822.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2016\"><\/a><\/p>\n<h4><a id=\"2016\"><\/a>2016<\/h4>\n<p>Guihard, P.J., Yao, J., Blazquez-Medela, A.M., <strong>Iruela-Arispe, M.L.<\/strong>, Bostrom, K.I., Yao, Y. 2016. <a href=\"http:\/\/journals.plos.org\/plosone\/article\/file?id=10.1371\/journal.pone.0167936&amp;type=printable\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial-Mesenchymal transition in vascular calcification of Ins2 Akita\/+ Mice<\/a> . PLoS One. 11(12):e0167936. PMCID: PMC5148029<\/p>\n<p>Shirali, A.S., McDonald, A.I., Mack, J.J., <strong>Iruela-Arispe, M.L.<\/strong> 2016. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ173.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Reproducible arterial denudation injury by infrarenal abdominal aortic clamping in a murine model<\/a>. J Vis Exp. Nov 24;(117), e54755.<\/p>\n<p>Inkeles, M.S., Teles, R.M., Pouldar, D., Andrade, P.R., Madigan, C.A., Lopez, D., Ambrose, M., Noursadeghi, M., Sarno, E.N., Rea, T.H., Ochoa, M.T., <strong>Iruela-Arispe, M.L.<\/strong>, Swindell, W.R., Ottenhoff, T.H., Geluk, A., Bloom, B.R., Pellegrini, M., Modlin, R.L. 2016. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5033757\/\" target=\"_blank\" rel=\"noopener noreferrer\">Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy<\/a>. JCI Insight. 1(15):e88843. PMCID: PMC5033757<\/p>\n<p>He, H., Mack, J.J., G\u00fcc, E., Warren, C.M., Squadrito, M.L., Kilarski, W.W., Baer, C., Freshman, R.D., McDonald, A.I., Ziyad, S., Swartz, M.A., De Palma, M., <strong>Iruela-Arispe, M.L.<\/strong> 2016. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ171.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Perivascular macrophages limit permeability<\/a>. ATVB. 36:2203-2212.<\/p>\n<p>Briot, A., Bouloumie, A., <strong>Iruela-Arispe, M.L.<\/strong> 2016. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5340259\/pdf\/nihms-851550.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Notch, lipids, and endothelial cells<\/a>. Curr Opin Lipidol. 27(5):513-20.<\/p>\n<p>Uebelhoer, M., <strong>Iruela-Arispe, M.L.<\/strong> 2016. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ169.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Cross-talk between signaling and metabolism in the vasculature.<\/a> Vascul Pharmacol. 83:4-9. PMCID: PMC4966612<\/p>\n<p>Youssef, K., Jarenwattananon, N., Archer, B., Mack, J., <strong>Iruela-Arispe, L.<\/strong>, Bouchard, L. 2016. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ168.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">4-D flow control in porous scaffolds: Toward a Next Generation of Bioreactors<\/a>. IEEE Trans Biomed Eng. 64(1):61-69.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2015\"><\/a><\/p>\n<h4><a id=\"2015\"><\/a>2015<\/h4>\n<p>Briot, A., Civelek, M., Seki, A., Hoi, K., Mack, J.J., Lee, S.D., Kim, J., Hong, C., Yu, J., Fishbein, G.A., Vakili, L., Fogelman, A.M., Fishbein M.C., Lusis, A.J., Tontonoz, P., Navab, M., Berliner, J.A., <strong>Iruela-Arispe, M.L.<\/strong> 2015. <a href=\"http:\/\/jem.rupress.org\/content\/212\/12\/2147.full.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis<\/a>. J Exp Med. 212(12):2147-63. PMCID: PMC4647265<\/p>\n<p>Rannou, E., Francois, A., Toullec, A., Guipaud, O., Buard, V., Tarlet, G., Mintet, E., Jaillet, C., <strong>Iruela-Arispe, M.L<\/strong>., Benderitter, M., Sabourin, J.C., Milliat, F. 2015. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4625166\/pdf\/srep15738.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury<\/a>. Sci Rep. 5:15738. PMCID: PMC4625166<\/p>\n<p>Hernandez-Garcia R, <strong>Iruela-Arispe ML<\/strong>, Reyes-Cruz G, Vazquez-Prado J. 2015. Endothelial RhoGEFs: <a href=\"http:\/\/ac.els-cdn.com\/S1537189115002207\/1-s2.0-S1537189115002207-main.pdf?_tid=2284b718-d9b4-11e5-add6-00000aacb362&amp;acdnat=1456180520_9ff94de3506c91a552c6e4b6ccf8c20d\" target=\"_blank\" rel=\"noopener noreferrer\">A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells<\/a>. Vascul Pharmacol. 74:60-72.<\/p>\n<p>Moughon D, He H, Schokrpur S, Jiang ZK, David J, Lin C, <strong>Iruela-Arispe ML<\/strong>, Dorigo O, Wu L. 2015. <a href=\"http:\/\/cancerres.aacrjournals.org\/content\/75\/22\/4742.full.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Macrophage blockade using CSF1R inhibitors reverses the vascular leakage underlying malignant ascites in late-stage epithelial ovarian cancer<\/a>. Cancer Res. 75:(22):4742-52. PMCID: PMC4675660<\/p>\n<p>McDonald AI, <strong>Iruela-Arispe ML<\/strong>. 2015. <a href=\"http:\/\/ac.els-cdn.com\/S153718911500138X\/1-s2.0-S153718911500138X-main.pdf?_tid=be1d8eb6-d9b4-11e5-97b5-00000aacb35d&amp;acdnat=1456180781_85d3bb8b76a27e2d1795e5bda635128a\" target=\"_blank\" rel=\"noopener noreferrer\">Healing arterial ulcers: Endothelial lining regeneration upon vascular denudation injury<\/a>. Vascul Pharmacol. 72:9-15. PMCID: PMC4547868<\/p>\n<p>Domigan CK, Warren CM, Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, <strong>Iruela-Arispe ML<\/strong>. 2015. <a href=\"http:\/\/jcs.biologists.org\/content\/joces\/128\/12\/2236.full.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy<\/a>. J Cell Sci. 128(12):2236-48. PMCID: PMC4487014<\/p>\n<p>Simons M, Alitalo K, Annex BH, Augustin HG, Beam C, Berk BC, Byzova T, Carmeliet P, Chilian W, Cooke JP, Davis GE, Eichmann A, <strong>Iruela-Arispe ML<\/strong>, Keshet E, Sinusas AJ, Ruhrberg C, Woo YJ, Dimmeler S; American Heart Assoc. Council on Basic Cardiovascular Sciences and Council on Cardiovascular Surgery and Anesthesia. 2015. <a href=\"http:\/\/circres.ahajournals.org\/content\/116\/11\/e99.full.pdf+html\" target=\"_blank\" rel=\"noopener noreferrer\">State-of-the-Art methods for evaluation of Angiogenesis and Tissue Vascularization: A scientific statement from the American Heart Association<\/a>. Circ Res. 116(11):e99-132.<\/p>\n<p>Rodriguez-Manzaneque, J.C., Fernandez- Rodriguez, R., Rodriguez-Baena, F.J., <strong>Iruela-Arispe, M.L<\/strong>.. 2015. <a href=\"http:\/\/ac.els-cdn.com\/S0945053X15000414\/1-s2.0-S0945053X15000414-main.pdf?_tid=b4ad0286-7bf8-11e5-994f-00000aacb362&amp;acdnat=1445874561_7f202dde5171b0b1cf913c92724cefa2\" target=\"_blank\" rel=\"noopener noreferrer\">ADAMTS proteases in vascular biology<\/a>. <span class=\"italics\"> Matrix Biol<\/span> 44-46:38-45.<\/p>\n<p>Briot, A., <strong>Iruela-Arispe, M.L<\/strong>.. 2015. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4342039\/\" target=\"_blank\" rel=\"noopener noreferrer\">Blockade of specific NOTCH ligands: a new promising approach in cancer therapy<\/a>. <span class=\"italics\"> Cancer Discov<\/span> 5: 112-114. PMCID: PMC4342039<\/p>\n<p>Domigan, C.K., Ziyad, S., <strong>Iruela-Arispe, M.L<\/strong>.. 2015. <a href=\"http:\/\/atvb.ahajournals.org\/content\/35\/1\/30.long\" target=\"_blank\" rel=\"noopener noreferrer\">Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction<\/a>. <span class=\"italics\"> Arterioscler Thromb Vasc Biol<\/span> 35: 30-39. PMCID: PMC4270848<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2014\"><\/a><\/p>\n<h4><a id=\"2014\"><\/a>2014<\/h4>\n<p><a id=\"2014\" href=\"https:\/\/www.mcdb.ucla.edu\/Research\/Arispe\/publications\/#2014\"><\/a>Briot, A., Jaroszewicz, A., Warren, C.M., Lu, J., Touma, M., Rudat, C., Hofmann, J.J., Airik, R., Weinmaster, G., Lyons, K., Wang, Y., Kispert, A., Pellegrini, M., <strong>Iruela-Arispe, M.L<\/strong>.. 2014. <a href=\"https:\/\/arispelab.mcdb.ucla.edu\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ157.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.<\/a> <span class=\"italics\"> Dev Cell<\/span> 31: 707-721. PMCID: PMC4311887<\/p>\n<p>Domigan, C.K., <strong>Iruela-Arispe, M.L<\/strong>.. 2014. <a href=\"http:\/\/ac.els-cdn.com\/S0092867414012951\/1-s2.0-S0092867414012951-main.pdf?_tid=a4fd92b0-7c02-11e5-8e80-00000aacb35e&amp;acdnat=1445878830_2e7f691824333d2cbfe6d49f4e0062d1\" target=\"_blank\" rel=\"noopener noreferrer\">Stealing VEGF from thy neighbor<\/a>. <span class=\"italics\"> Cell<\/span> 159: 473-474.<\/p>\n<p>Warren, C.M., <strong>Iruela-Arispe, M.L<\/strong>.. 2014. <a href=\"http:\/\/www.nature.com\/ncb\/journal\/v16\/n10\/pdf\/ncb3044.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Podosome rosettes precede vascular sprouts in tumour angiogenesis<\/a>. <span class=\"italics\">Nat Cell Biol<\/span> 16: 928-930.<\/p>\n<p>Nowak-Sliwinska, P., Segura, T., <strong>Iruela-Arispe, M.L<\/strong>.. 2014. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4583126\/\" target=\"_blank\" rel=\"noopener noreferrer\">The chicken chorioallantoic membrane model in biology, medicine and bioengineering<\/a>. <span class=\"italics\"> Angiogenesis<\/span> 17: 779-804.<\/p>\n<p>Michael, I.P., Westenskow, P.D., Hacibekiroglu, S., Greenwald, A.C., Ballios, B.G., Kurihara, T., Li, Z., Warren, C.M., Zhang, P., Aguilar, E., Donaldson, L., Marchetti, V., Baba, T., Hussein, S.M., Sung, H.K., <strong>Iruela-Arispe, M.L<\/strong>., Rini, J.M., van der Kooy, D., Friedlander, M., Nagy, A.. 2014. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4023884\/\" target=\"_blank\" rel=\"noopener noreferrer\">Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye<\/a>. <span class=\"italics\"> EMBO Mol Med<\/span> 6: 604-623.<\/p>\n<p>Goddard, L.M., Murphy, T.J., Org, T., Enciso, J.M., Hashimoto-Partyka, M.K., Warren, C.M., Domigan, C.K., McDonald, A.I., He, H., Sanchez, L.A., Allen, N.C., Orsenigo, F., Chao, L.C., Dejana, E., Tontonoz, P., Mikkola, H.K., <strong>Iruela-Arispe, M.L<\/strong>.. 2014. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3985399\/\" target=\"_blank\" rel=\"noopener noreferrer\">Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation<\/a>. <span class=\"italics\"> Cell<\/span> 156: 549-562.<\/p>\n<p>Griffin, D.R., Borrajo, J., Soon, A., Acosta-Velez, G.F., Oshita, V., Darling, N., Mack, J., Barker, T., <strong>Iruela-Arispe, M.L<\/strong>., Segura, T.. 2014. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4024472\/\" target=\"_blank\" rel=\"noopener noreferrer\">Hybrid photopatterned enzymatic reaction (HyPER) for in situ cell manipulation<\/a>. <span class=\"italics\"> Chemobiochem<\/span> 15: 233-242.<\/p>\n<p>Warren, C.M., Ziyad, S., Briot, A., Der, A., <strong>Iruela-Arispe, M.L<\/strong>.. 2014. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4030697\/\" target=\"_blank\" rel=\"noopener noreferrer\">A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes<\/a>. <span class=\"italics\"> Science Signaling<\/span> 7: 233-242.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2013\"><\/a><\/p>\n<h4><a id=\"2013\"><\/a>2013<\/h4>\n<p>Milde, F., Lauw, S. Koumoutsakos, P., and <strong>Iruela-Arispe, M.L<\/strong>.. 2013. <a href=\"https:\/\/arispelab.mcdb.ucla.edu\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ149.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">The mouse retina in 3D: quantification of vascular growth and remodeling<\/a>. <span class=\"italics\"> Integrative Biology<\/span> : 233-242.<\/p>\n<p>Turlo, K.A., Scapa, J., Bagher, P., Jones, A.W., Feil, R., Korthuis, R.J., Segal, S.S., <strong>Iruela-Arispe, M.L.<\/strong>. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3882010\/\" target=\"_blank\" rel=\"noopener noreferrer\">Beta1-Integrin is essential for vasoregulation and smooth muscle survival In Vivo<\/a>. <span class=\"italics\"> Arterioscler Thromb Vasc Biol<\/span> 33: 2325-2335.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Beitel, G.J.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3699276\/\" target=\"_blank\" rel=\"noopener noreferrer\">Tubulogenesis<\/a>. <span class=\"italics\"> Development<\/span> 140: 2851-2855.<\/p>\n<p>Corada, M., Orsenigo, F., Morini, M.F., Pitulescu, M.E., Bhat, G., Nyqvist, D., Breviario F., Conti, V., Briot, A., <strong>Iruela-Arispe, M.L.<\/strong>, Adams, R.H., Dejana, E. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3826640\/pdf\/ncomms3609.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Sox17 is indispensable for acquisition and maintenance of arterial identity<\/a>. Nat. Commun. 4:2609. PMCID: PMC3826640<\/p>\n<p><a id=\"2013\" href=\"https:\/\/www.mcdb.ucla.edu\/Research\/Arispe\/publications\/#2014\"><\/a>Goddard, L.M., Ton, A.M., Org, T., Mikkola, H.K., <strong>Iruela-Arispe, M.L<\/strong>.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3819224\/pdf\/nihms507579.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Selective suppression of endothelial cytokine production by progesterone receptor<\/a>. <span class=\"italics\"> Vascul. Pharmacol<\/span> 59: 36-43 . PMCID: PMC3819224<\/p>\n<p>Janzen, D.M., Rosales, M.A., Paik, D.Y., Lee, D.S., Smith, D.A., Witte, O.N., <strong>Iruela-Arispe, M.L<\/strong>., Memarzadeh, S.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3752407\/pdf\/nihms-489574.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy<\/a>. <span class=\"italics\"> Cancer Res<\/span> 73: 4697-4710. PMCID: PMC3752407<\/p>\n<p>Roodhart, J.M.L., He, H., Daenen, L.G.M., Monvoisin, A., Barber, C., van Amersfoort, M., Hofmann, J.J., Radtke, F., Lane, T.F., Voest, E.E., <strong>Iruela-Arispe, M.L<\/strong>.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3701902\/\" target=\"_blank\" rel=\"noopener noreferrer\">Notch1 regulates angio-supportive bone-marrow-derived cells in mice: relevance to chemoresistance<\/a>. <span class=\"italics\"> Blood<\/span> 122: 143-153. PMCID: PMC3701902<\/p>\n<p>Baer, C., Squadrito, M.L., <strong>Iruela-Arispe, M.L<\/strong>., De Palma, M.. 2013. <a href=\"http:\/\/ac.els-cdn.com\/S0014482713001341\/1-s2.0-S0014482713001341-main.pdf?_tid=6f13ea6a-7c0b-11e5-a495-00000aacb35d&amp;acdnat=1445882605_cdd8d7d7564001e63ba71bb79b979379\" target=\"_blank\" rel=\"noopener noreferrer\">Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches<\/a>. <span class=\"italics\"> Exp Cell Res<\/span> 319: 1626-1634.<\/p>\n<p>Cristofaro, B., Shi, Y., Faria, M., Suchting, S., Leroyer, A.S., Trindade, A., Duarte, A., Zovein, A.C., <strong>Iruela-Arispe, M.L<\/strong>., Nih, L.R., Kubis, N., Henrion, D., Loufrani, L., Todiras, M., Schleifenbaum, J., Gollasch, M., Zhuang, Z.W., Simons, M., Eichmann, A., le Noble, F.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4074271\/\" target=\"_blank\" rel=\"noopener noreferrer\">Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models<\/a>. <span class=\"italics\"> Development<\/span> 140: 1720-1729. PMCID: PMC4074271<\/p>\n<p>Goddard, L.M., <strong>Iruela-Arispe, M.L<\/strong>.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3786592\/pdf\/nihms473613.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Cellular and molecular regulation of vascular permeability<\/a>. <span class=\"italics\"> Thromb. Haemost<\/span> 109: 407-415. PMCID: PMC3786592<\/p>\n<p>Defalco, T., Saraswathula, A., Briot, A., <strong>Iruela-Arispe, M.L<\/strong>., Capel, B.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4013875\/pdf\/bire_88_04_0091.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Testosterone levels influence mouse fetal leydig cell progenitors through Notch signaling<\/a>. <span class=\"italics\">Biol. Reprod<\/span> 88: 1-12. PMCID: PMC4013875<\/p>\n<p>Mack, J.J., Youssef, K., Noel, O.D., Lake, M.P., Wu, A., <strong>Iruela-Arispe, M.L<\/strong>., Bouchard, L.S.. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3714210\/pdf\/nihms475365.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Real-time maps of fluid flow fields in porous biomaterials.<\/a> B<span class=\"italics\">iomaterials<\/span> 34: 1980-86. PMCID: PMC3714210<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2012\"><\/a><\/p>\n<h4><a id=\"2012\"><\/a>2012<\/h4>\n<p>Domigan, C.K., <strong>Iruela-Arispe, M.L<\/strong>.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3666551\/pdf\/nihms452964.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Recent advances in vascular development<\/a>. <span class=\"italics\">Curr Opin Hematol<\/span> 19: 176-183. PMCID: PMC3666551<\/p>\n<p>Howell, M.D., Torres-Collado, A.X., <strong>Iruela-Arispe, M.L<\/strong>., Gottschall, P.E.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3469530\/pdf\/pone.0047226.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Selective decline of synaptic protein levels in the frontal cortex of female mice deficient in the extracellular metalloproteinase ADAMTS1<\/a>. <span class=\"italics\">PLoS One<\/span> 7: e47226. PMCID: PMC3469530<\/p>\n<p>Hofmann, J.J., Briot, A., Enciso, J., Zovein, A.C., Ren, S., Zhang, Z.W., Radtke, F., Simons, M., Wang, Y., <strong>Iruela-Arispe, M.L<\/strong>.. 2012. <a href=\"http:\/\/dev.biologists.org\/content\/139\/23\/4449\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial deletion of murine Jagged1 leads to valve calcification and congenital heart defects associated with Alagille syndrome<\/a>. <span class=\"italics\">Development<\/span> 139: 4449-4460. PMCID: PMC3509736<\/p>\n<p>He, H., Xu, J., Warren, C.M., Duan, D., Wu, L., <strong>Iruela-Arispe, M.L<\/strong>.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3471522\/\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages<\/a>.<span class=\"italics\"> Blood<\/span> 120: 3152-3162. PMCID: PMC3471522<\/p>\n<p>Avraham-Davidi, I., Ely, Y., Pham, V.N., Castranova, D., Grunspan, M., Malkinson, G., Gibbs-Bar, L., Mayseless, O., Allmog, G., Lo, B., Warren, C.M., Chen, T.T., Ungos, J., Kidd, K., Shaw, K., Rogachev, I., Wan, W., Murphy, P.M., Farber, S.A., Carmel, L., Shelness, G.S., <strong>Iruela-Arispe, M.L<\/strong>., Weinstein, B.M., Yaniv, K.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3959651\/pdf\/nihms475364.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor-1<\/a>. <span class=\"italics\"> Nat. Med<\/span> 18: 967-973. PMCID: PMC3959651<\/p>\n<p>Chhabra, A., Lechner, A.J., Ueno, M., Acharya, A., van Handel, B., Wang, Y., <strong>Iruela-Arispe, M.L<\/strong>., Tallquist, M.D., Mikkola, H.K.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3395466\/pdf\/nihms362479.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling<\/a>. <span class=\"italics\"> Dev. Cell<\/span> 13: 651-659. PMCID: PMC3395466<\/p>\n<p>Hall-Glenn, F., De Young, R.A., Huang, B.L., van Handel, B., Hofmann, J.J., Chen, T.T., Choi, A., Ong, J.R., Benya, P.D., Mikkola, H., <strong>Iruela-Arispe, M.L<\/strong>., Lyons, K.M.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3282727\/pdf\/pone.0030562.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">CCN2\/Connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis<\/a>. <span class=\"italics\">PLoS One<\/span> 7: e30562. PMCID: PMC3282727<\/p>\n<p>Turlo, K.A., Noel, O.D., Vora, R., LaRussa, M., Hall-Glenn, F., <strong>Iruela-Arispe, M.L<\/strong>.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3590017\/pdf\/nihms365849.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">An essential requirement for Beta-1 integrin in the assembly of extracellular matrix proteins within the vascular wall<\/a>. <span class=\"italics\"> Dev. Biol<\/span> 365: 23-35. PMCID: PMC3590017<\/p>\n<p>Cooley,M.A., Fresco, V.M., Dorlon, M.E., Twal, W.O., Lee, N.V., Barth, J.L., Kern, C.B., <strong>Iruela-Arispe, M.L<\/strong>., Argraves, W.S.. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3489172\/pdf\/nihms398781.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1\/2 activation, and to attenuate trabecular cardiomyocyte proliferation<\/a>. <span class=\"italics\">Dev. Dyn<\/span> 241: 303-314. PMCID: PMC3489172<\/p>\n<p>Scheppke, L., Murphy, E., Zarpellon, A., Hofmann, J.J., Merkulova, A., Shields, D., Weis, S., Byzova, T., Ruggeri, Z., <strong>Iruela-Arispe, M.L.<\/strong>, Cheresh, D. 2012. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3311249\/\" target=\"_blank\" rel=\"noopener noreferrer\">Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane<\/a>. <span class=\"italics\">Blood<\/span> 119: 2149-2158. PMCID: PMC3311249<\/p>\n<p>Youssef, K., Mack, J.J., <strong>Iruela-Arispe, M.L<\/strong>., Bouchard, L.S.. 2012. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bit.24440\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Macro-scale topology optimization for controlling internal shear stress in a porous scaffold bioreactor<\/a>. <span class=\"italics\"> Biotechnol. Bioeng<\/span> 109: 1844-1854.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2011\"><\/a><\/p>\n<h4><strong>2011<\/strong><\/h4>\n<p>Ziyad, S., <strong>Iruela-Arispe, M.L<\/strong>.. 2011. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3411131\/pdf\/10.1177_1947601911432334.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Molecular mechanisms of tumor angiogenesis<\/a>. <span class=\"italics\"> Genes and Cancer. 2(12)<\/span>: 1085-96. PMCID: PMC3411131<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>. 2011. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3099250\/pdf\/nihms289452.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">LUMENating blood vessels<\/a>. <span class=\"italics\">Dev. Cell<\/span> 20: 412-414. PMCID: PMC3099250<\/p>\n<p>Anderson, S.M., Shergill, B., Barry, Z.T., Manousiouthakis, E., Chen, T.T., Botvinick, E., Platt, M.O., <strong>Iruela-Arispe, M.L<\/strong>., and Segura, T. 2011. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3621282\/pdf\/nihms333074.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF<\/a>. <span class=\"italics\"> Integrative Biology<\/span> 3: 887-896. PMCID: PMC3621282<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2010\"><\/a><\/p>\n<h4><a id=\"2010\"><\/a>2010<\/h4>\n<p>Corada, M., Nyqvist, D., Orsenigo, F., Caprini, A., Giampietro, C., Taketo, M.M., <strong>Iruela-Arispe, M.L<\/strong>., Adams, R.H., Dejana, E.. 2010. <a href=\"http:\/\/ac.els-cdn.com\/S1534580710002145\/1-s2.0-S1534580710002145-main.pdf?_tid=7211bb3a-7c32-11e5-b9b0-00000aacb361&amp;acdnat=1445899360_e35bfb4751734809ebbf765781ff1c71\" target=\"_blank\" rel=\"noopener noreferrer\">The Wnt\/beta-catenin pathway modulates vascular remodeling and specification by upregulating DII4\/Notch signaling<\/a>. <span class=\"italics\"> Dev. Cell<\/span> 18: 938-949.<\/p>\n<p>Hofmann, J.J., Zovein, A.C., Koh, H., Radtke, F., Weinmaster, G., and <strong>Iruela-Arispe, M.L<\/strong>.. 2010. <a href=\"http:\/\/dev.biologists.org\/content\/137\/23\/4061\" target=\"_blank\" rel=\"noopener noreferrer\">Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome<\/a>. <span class=\"italics\"> Development<\/span> 137: 4061-4072. PMCID: PMC2976287<\/p>\n<p>Turlo, K.A., Gallaher, S.D., Vora, R., Laski, F.A., <strong>Iruela-Arispe, M.L<\/strong>.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2975293\/pdf\/GEN1863959.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">When Cre-mediated recombination in mice does not result in protein loss<\/a>. <span class=\"italics\"> Genetics (highlighted by Journal)<\/span> 186: 959-967. PMCID: PMC2975293<\/p>\n<p>Zovein, A.C., Turlo, K.A., Ponec, R.M., Lynch, M.R., Chen, K.C., Hofmann, J.J., Cox, T.C., Gasson, J.C., <strong>Iruela-Arispe, M.L<\/strong>.. 2010. <a href=\"http:\/\/www.bloodjournal.org\/content\/bloodjournal\/116\/18\/3435.full.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular remodeling of the vitelline artery initiates extra-vascular emergence of hematopoietic clusters<\/a>. <span class=\"italics\"> Blood (Cover)<\/span> 116: 3435-3444.<\/p>\n<p>Da Silva, R.G., Tavora, B., Robinson, S.D., Reynolds, L.E., Szekeres, C., Lamar, J., Batista, S., Kotourou, V., Germain, M.A., Reynolds, A.R., Jones, D.T., Watson, A.R., Jones, J.L., Harris, A., Hart, I.R., <strong>Iruela-Arispe, M.L<\/strong>., Dipersion, C.M., Kreidberg, J.A., Hodivala-Dilke, K.M.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2928983\/pdf\/JPATH177001534.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial alpha 3 beta1 integrin represses pathological angiogenesis and sustains endothelial VEGF<\/a>. <span class=\"italics\"> Am. J. Pathol<\/span> 177: 1534-1548. PMCID: PMC2928983<\/p>\n<p>Warren, C.M., and <strong>Iruela-Arispe, M.L<\/strong>.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2921923\/pdf\/nihms-203534.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Signaling circuitry in vascular morphogenesis<\/a>. <span class=\"italics\"> Curr Opin Hematol<\/span> 17: 213-218. PMCID: PMC2921923<\/p>\n<p>Arroyo, A.G., and <strong>Iruela-Arispe, M.L<\/strong>.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2856193\/pdf\/cvq049.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Extracellular matrix, inflammation, and the angiogenic response<\/a>. <span class=\"italics\"> Cardiovasc Res<\/span> 86: 226-235. PMCID: PMC2856193<\/p>\n<p>Chen, T.T., Luque, A., Lee, S., Anderson, S.M., Segura, T., <strong>Iruela-Arispe, M.L.<\/strong>. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2828913\/pdf\/JCB_200906044.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells<\/a>. <span class=\"italics\"> J Cell Biol<\/span> 188: 595-609. PMCID: PMC2828913<\/p>\n<p>Zovein, A.C., Luque, A., Turlo, K.A., Hofmann, J.J., Yee, K.M., Becker, M.S., Fassler, R., Mellman, I., Lane, T.F., <strong>Iruela-Arispe, M.L<\/strong>.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3178410\/pdf\/nihms165067.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism<\/a>. <span class=\"italics\"> Dev. Cell<\/span> 18: 39-51. PMCID: PMC3178410<\/p>\n<p>Stockman, C., Kerdiles, Y., Nomaksteinsky, M., Weidemann, A., Takeda, N., Doedens, A., Torres-Collado, A.X., <strong>Iruela-Arispe, M.L.<\/strong>, Nizet, V., Johnson, R.S.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2840078\/pdf\/pnas.200912766.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis<\/a>. <span class=\"italics\"> Proc Natl Acad Sci USA<\/span> 107: 4329-4334. PMCID: PMC2840078<\/p>\n<p>Lee, Y.J., Koch, M., Karl, D., Torres-Collado, A.X., Fernando, N.T., Rothrock, C., Kuruppu, D., Ryeom, S., <strong>Iruela-Arispe, M.L<\/strong>., Yoon, S.S.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2934910\/pdf\/nihms163392.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1<\/a>.<span class=\"italics\"> Cancer Res<\/span> 70: 948-956. PMCID: PMC2934910<\/p>\n<p>Priceman, S.J., Sung, J.L., Shaposhnik,, Z., Burton, J.B., Torres-Collado, A.X., Moughon, D.L., Johnson, M., Lusis, A.J., Cohen, D.A., <strong>Iruela-Arispe, M.L<\/strong>., and Wu, L.. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2826767\/\" target=\"_blank\" rel=\"noopener noreferrer\">Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of anti-angiogenic of anti-angiogenic therapy<\/a>. <span class=\"italics\"> Blood<\/span> 115: 1461-471. PMCID: PMC2826767<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., and Lee, S.. 2010. <a href=\"https:\/\/arispelab.mcdb.ucla.edu\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ2010Chap235.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Mechanisms underlying context-dependent VEGF signaling for distinct biological responses<\/a>. <span class=\"italics\"> Handbook of Cell Signaling, Second Ed.<\/span>: 1919-1925.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2009\"><\/a><\/p>\n<h4><a id=\"2009\"><\/a>2009<\/h4>\n<p>Zovein, A.C., and <strong>Iruela-Arispe, M.L<\/strong>.. 2009. <a href=\"http:\/\/ac.els-cdn.com\/S1934590909004482\/1-s2.0-S1934590909004482-main.pdf?_tid=33f4bc06-7cc0-11e5-af1e-00000aab0f02&amp;acdnat=1445960245_b41b01c0e8765b2e11165ba1b13639cb\" target=\"_blank\" rel=\"noopener noreferrer\">Time to cut the cord: placental HSCs grow up<\/a>. <span class=\"italics\"> Cell Stem Cell<\/span> 5: 351-352.<\/p>\n<p>Skuli, N., Liu, L., Runge, A., Wang, T., Yuan, L., Patel, S., <strong>Iruela-Arispe, M.L<\/strong>., Simon, M.C., Keith, B.. 2009. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2714217\/\" target=\"_blank\" rel=\"noopener noreferrer\">Endothelial deletion of hypoxia-inducible factor-2alpha(HIF-2alpha) alters vascular function and tumor angiogenesis<\/a>. <span class=\"italics\"> Blood<\/span> 114: 469-477. PMCID: PMC2714217<\/p>\n<p>Anderson, S.M., Chen, T.T., <strong>Iruela-Arispe, M.L<\/strong>., Segura, T.. 2009. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2826152\/pdf\/nihms170955.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF<\/a>. <span class=\"italics\"> Biomaterials<\/span> 30: 4618-4628. PMCID: PMC2826152<\/p>\n<p>Speck, N.A., <strong>Iruela-Arispe, M.L<\/strong>.. 2009. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2723839\/pdf\/nihms125104.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Conditional Cre\/LoxP Strategies for the Study of Hematopoietic Stem Cell Formation<\/a>. <span class=\"italics\"> Blood Cells Mol. Dis<\/span> 43: 6-11. PMCID: PMC2723839<\/p>\n<p>Rodriguez-Manzaneque, J.C., Carpizo, D., Plaza-Calonge, M.D., Torres-Collado, A.X., Thai, S.N., Simons, M., Horowitz, A., and <strong>Iruela-Arispe, M.L<\/strong>.. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3807939\/pdf\/nihms494873.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion<\/a>. <span class=\"italics\"> Int. J. Biochem. Cell Biol. 41:800-810<\/span>. PMCID: PMC3807939<\/p>\n<p><strong>Iruela-Arispe, M.L., <\/strong>Davis, G.E. 2009. <a href=\"http:\/\/ac.els-cdn.com\/S1534580709000410\/1-s2.0-S1534580709000410-main.pdf?_tid=2dff88f4-7cc9-11e5-98dc-00000aacb35d&amp;acdnat=1445964100_b8f324019b760e3aa1baf9e8527af622\" target=\"_blank\" rel=\"noopener noreferrer\">Cellular and molecular mechanisms of vascular lumen formation<\/a>. Dev Cell. 16:222-31.<\/p>\n<p><a id=\"2008\"><\/a> 2008<\/p>\n<p><strong>Iruela-Arispe, M.Luisa<\/strong>. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3010394\/pdf\/nihms254392.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Regulation of Thrombospondin1 by Extracellular Proteases<\/a>.<span class=\"italics\"> Current Drug Targets<\/span> 9: 863-868. PMCID: PMC3010394<\/p>\n<p>Zovein, A.C. Hofmann, J.J., Lynch, M., French, W.J., Turlo, K.A., Yang, Y., Becher, M.S., Zanetta, L., Dejana, E., Gasson, J. Tallquist, M.D., and <strong>Iruela-Arispe, M.L<\/strong>.. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2631552\/pdf\/nihms84026.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Fate tracing reveals the endothelial origin of hematopoietic stem cells<\/a>. <span class=\"italics\"> Cell Stem Cell<\/span> 3: 625-636. PMCID: PMC2631552<\/p>\n<p>Suarez, Y., Fernandez-Hernando, C., Yu, J., Gerber, S.A., Harrison, K.D., Pober, J.S. <strong>Iruela-Arispe, M.L<\/strong>., Merkernschlager, M., and Sessa, W.C.. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2544582\/pdf\/zpq14082.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis<\/a>. <span class=\"italics\"> PNAS<\/span> 105: 14082-14087. PMCID: PMC2544582<\/p>\n<p>Guo, W., Lasky, J.L., Chang, C.J., Mosessian, S., Lewis, X., Xiao, Y., Yeh, J.E., Chen, J. Y., <strong>Iruela-Arispe, M.L.<\/strong>, Varella-Garcia, M., and Wu, H.. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2840044\/pdf\/nihms-174213.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Multi-genetic events collaboratively contribute to Pten-deficient leukemia stem-cell formation<\/a>. <span class=\"italics\">Nature<\/span> 453:529-533. PMCID:PMC2840044<\/p>\n<p>Stankunas, K. Hang, C.T., Tsun, Z.Y. Chen, H., Lee, N.V., Wu, J.I., Shang, C., Bayle, J.H., Shou, W., <strong>Iruela-Arispe, M.L<\/strong>., and Chang, C.P.. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2274005\/pdf\/nihms-40729.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis<\/a>. <span class=\"italics\"> Dev. Cell<\/span> 14: 298-311. PMCID: PMC2274005<\/p>\n<p>Misra, S., Lee, N. Fu, A.A., Raghavakaimal, S., Mandrekar, J., Bjarnason, H., McKusick, M.A., <strong>Iruela-Arispe, L<\/strong>., Mukhopadhyay, D.. 2008. <a href=\"http:\/\/ac.els-cdn.com\/S1051044307012699\/1-s2.0-S1051044307012699-main.pdf?_tid=9cf8bd2c-7ccc-11e5-bfb2-00000aab0f6c&amp;acdnat=1445965575_765bcad277c385503be25e671d9bd35f\" target=\"_blank\" rel=\"noopener noreferrer\">Increased expression of a disintegrin and metalloproteinase thrombospondin 1 in thrombosed hemodialysis grafts<\/a>. <span class=\"italics\"> J. Vasc. Interv. Radiol<\/span> 19: 111-119.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>.. 2008.Endothelial Cell Activation. Chapter in: Angiogenesis: <a href=\"https:\/\/arispelab.mcdb.ucla.edu\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ2008Chap3.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">An Integrative Approach from Science to Medicine<\/a>. Springer, Editors: Judah Folkman and J. Figg, 35-43.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2007\"><\/a><\/p>\n<h4><a id=\"2007\"><\/a>2007<\/h4>\n<p>Lundkvist, A., Lee, S., <strong>Iruela-Arispe, L<\/strong>., Betsholtz, C., Gerhardt, H.. 2007. Growth factor gradients in vascular patterning. <span class=\"italics\">Novartis Found. Symp<\/span> 283: 194-201.<\/p>\n<p>Lee, S. and <strong>Iruela-Arispe, M.L<\/strong>.. 2007. <a href=\"https:\/\/arispelab.mcdb.ucla.edu\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ2007LeeSChap5.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">The Extracellular Matrix and VEGF Processing<\/a> <span class=\"italics\"> Anti-Angiogenesis, 2nd edition<\/span> : 194-201.<\/p>\n<p>Hofmann, J.J. and <strong>Iruela-Arispe M.L.<\/strong>. 2007. Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis. <span class=\"italics\"> Gene Expr Patterns<\/span> 7: 461-470. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/HofmannGeneExprPat_2007.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">HofmannGeneExprPat_2007<\/a><\/p>\n<p>Lee, M., Chen, T.T., <strong>Iruela-Arispe, M.L<\/strong>., Wu, B.M., Dunn, J.C.. 2007. Modulation of protein delivery from modular polymer scaffolds. <span class=\"italics\">Biomaterials<\/span> 28: 1862-1870. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/LeeM_Biomaterials_2007.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">LeeM_Biomaterials_2007<\/a><\/p>\n<p>Hellstrom, M., Phng, L.K., Hofmann, J.J., Wallgard, E., Coultas, L., Lindblom, P., Alva, J., Nilsson, A.K., Karlsson, L., Gaiano, N., Yoon, K., Rossant, J., <strong>Iruela-Arispe, M.L<\/strong>., Kalen, M., Gerhardt, H., Betsholtz, C.. 2007. D114\/Notch1 regulates formation of tip cells during angiogenesis. <span class=\"italics\">Nature<\/span> 445: 776-780. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Hellstrom_Nature_2007.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Hellstrom_Nature_2007<\/a><\/p>\n<p>Hofmann, J.J., <strong>Iruela-Arispe, M.L<\/strong>.. 2007. Notch signaling in blood vessels: who is talking to whom about what? <span class=\"italics\"> Circulation Res<\/span> 100: 1556-1568. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Publ93.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Hofmann_2007<\/a><\/p>\n<p>Lee, S., Chen, T.T., Barber, C.L., Jordan, M.C., Murdock, J., Desai, S., Ferrara, N., Nagy, A., Roos, K.P. and <strong>Iruela-Arispe, M.L<\/strong>.. 2007. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3010851\/pdf\/nihms254111.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Autocrine VEGF Signaling Is Required for Vascular Homeostasis<\/a>. <span class=\"italics\">Cell<\/span> 130: 691-703. PMCID: PMC3010851<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2006\"><\/a><\/p>\n<h4><a id=\"2006\"><\/a>2006<\/h4>\n<p>Lee, N.V. and <strong>Iruela-Arispe, M.L<\/strong>.. 2006. <a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-540-33177-3_13\" target=\"_blank\" rel=\"noopener noreferrer\">Thrombospondins and Angiogenesis <span class=\"italics\"> Tumor Angiogenesis: Mechanisms and Cancer Therapy<\/span><\/a> : 233-245.<\/p>\n<p>Zovein, A.C. and <strong>Iruela-Arispe, M.L.<\/strong>. 2006. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1559733\/pdf\/zpq12959.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">My O\u2019Myeloid, a tale of two lineages<\/a>. <span class=\"italics\"> PNAS<\/span> 103: 12959-12960. PMCID: PMC1559733<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>.. 2006. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1698778\/pdf\/JPATH169000347.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">When it comes to lymphatics, it is all a question of time<\/a>. <span class=\"italics\"> Am J. Pathol<\/span> 169: 347-350. PMCID: PMC1698778<\/p>\n<p>Barber, C.L., and <strong>Iruela-Arispe, M.L<\/strong>.. 2006. <a href=\"http:\/\/www.nature.com\/pr\/journal\/v59\/n4s\/pdf\/pr2006123a.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">The ever-Elusive Endothelial Progenitor Cell: Identities, Functions and Clinical Implications<\/a>. <span class=\"italics\">Pediatr Res<\/span> 59: 26-32.<\/p>\n<p>Alva, J.A., Zovein, A.C., Monvoisin, A., Murphy, T., Salazar, A., Harvey, N.L., Carmeliet, P. and <strong>Iruela-Arispe, M.L<\/strong>.. 2006. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dvdy.20643\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">VE-Cadherin-Cre-recombinase transgenic mouse: A tool for lineage analysis and gene deletion in endothelial cells<\/a>. <span class=\"italics\"> Dev Dyn<\/span> 235: 759-767.<\/p>\n<p>Yang, L.V., Radu, C.G., Roy, M., Lee, S., McLaughlin, J., Teitell, M.A., <strong>Iruela-Arispe M.L<\/strong>. and Witte, O.N.. 2006. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1800706\/pdf\/1909-06.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor<\/a>. <span class=\"italics\"> Mol Cell Biol<\/span> 27: 1334-1347. PMCID: PMC1800706<\/p>\n<p>Kern, C.B., Twal, W.O., Mjaatvedt, C.H., Fairey, S.E., Toole, B.P., <strong>Iruela-Arispe, M.L<\/strong>., Argraves, W.S. 2006. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1828280\/pdf\/nihms18799.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Proteolytic cleavage of versican during cardiac cushion morphogenesis<\/a>. <span class=\"italics\">Dev Dyn<\/span> 235: 2238-2247. PMCID: PMC1828280<\/p>\n<p>Torres-Collado, A.X., Kisiel, W., <strong>Iruela-Arispe, M.L<\/strong>., Rodriguez-Manzaneque, J.C. 2006. <a href=\"http:\/\/www.jbc.org\/content\/281\/26\/17827.long\" target=\"_blank\" rel=\"noopener noreferrer\">ADAMTS1 interacts with, cleaves and modifies the extracellular location of the matrix inhibitor tissue factor pathway inhibitor-2 (TFPI-2)<\/a>. <span class=\"italics\">J Biol Chem<\/span> 281: 17827-17837.<\/p>\n<p>Monvoisin, A., Alva, J.A., Hofmann, J.J., Zovein, A.C., Lane, T.F., and <strong>Iruela-Arispe, M.L<\/strong>. 2006. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dvdy.20982\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">VE-cadherin-CreER(T2) transgenic mice: A model for inducible recombination in the endothelium<\/a>. <span class=\"italics\"> Dev. Dyn<\/span> 235: 3413-3422.<\/p>\n<p>Lee, N.V., Sato, M., Annis, D.S., Loo, J.A., Wu, L., Mosher, D.F. and <strong>Iruela-Arispe, M.L.<\/strong> 2006. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1636613\/pdf\/7601400a.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">ADAMTS1 mediates the release of anti-angiogenic polypeptides from TSP1 and TSP2<\/a>. <span class=\"italics\"> The EMBO J<\/span> 25: 5270-5283. PMCID: PMC1636613<\/p>\n<p>Hashimoto-Partyka, M., Lydon, J., and <strong>Iruela-Arispe, M.L<\/strong>. 2006. Generation of a mouse for conditional excision of progesterone receptor (PRCE). <span class=\"italics\"> Genesis<\/span> 44: 391-395. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/genesis_44.391.2006.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">genesis_(44).391.2006<\/a><\/p>\n<p>Lee, N.V., Rodriguez-Manzaneque, J.C., Thai, S.N., Twal, W.O., Luque, A., Lyons, K.M., Argraves, W.S., <strong>Iruela-Arispe, M.L<\/strong>. 2005. <a href=\"http:\/\/www.jbc.org\/content\/280\/41\/34796.long\" target=\"_blank\" rel=\"noopener noreferrer\">Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1<\/a>. <span class=\"italics\">J Biol Chem<\/span> 280: 34796-34804.<\/p>\n<p>Cho, H.M., Rosenblatt, J.D., Kang, Y.S., <strong>Iruela-Arispe, M.L.<\/strong>, Morrison, S.L., Penichet, M.L., Kwon, Y.G., Kim, T.W., Webster, K.A., Nechustan, H. and Shin, S.U. 2005. <a href=\"http:\/\/mct.aacrjournals.org\/content\/4\/6\/956.long\" target=\"_blank\" rel=\"noopener noreferrer\">Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein<\/a>. <span class=\"italics\"> Mol Cancer Ther<\/span> 4: 956-967.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2005\"><\/a><\/p>\n<h4><a id=\"2005\"><\/a>2005<\/h4>\n<p><strong>Iruela-Arispe, M.L<\/strong>. 2005. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/vasdev_angio_2005.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular Development and Angiogenesis <span class=\"italics\"> Book Title: Encyclopedia of Molecular Cell Biology and Molecular Medicine<\/span><\/a> : 201-232. vasdev_angio_2005<\/p>\n<p>Lee, S., Jilani, S.M. Nikolova, G.V., Carpizo, D., and <strong>Iruela-Arispe, M.L<\/strong>. 2005. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2171712\/pdf\/200409115.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors<\/a>. <span class=\"italics\">J Cell Biol<\/span> 169:681-691. PMCID: PMC2171712<\/p>\n<p>Krampert, M., Kuenzle, S., Thai, S.N., Lee, N., <strong>Iruela-Arispe, M.L.<\/strong>, Werner, S. 2005. ADAMTS1 proteinase is upregulated in wounded skin and regulates migration of fibroblasts and endothelial cells. <span class=\"italics\">J Biol Chem<\/span> 280: 23844-23852. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Krampert_jbc_2802005.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Krampert_jbc_280(2005)<\/a><\/p>\n<p><a class=\"mwm-aal-item\" name=\"2004\"><\/a><\/p>\n<h4><a id=\"2005\"><\/a>2004<\/h4>\n<p>Thomas-Tikkonenko, A. and <strong>Iruela-Arispe, M.L<\/strong>.. 2004. Whence Thrombospondin? <span class=\"italics\"> Cancer Biology and Therapy<\/span> 3: 406-7. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/ThomasTikhonenko2004.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">ThomasTikhonenko(2004)<\/a><\/p>\n<p>Alva, J.A. and <strong>Iruela-Arispe, M.L<\/strong>.. 2004. Notch Signaling in Vascular Morphogenesis. <span class=\"italics\">Current Opinion in Hematology<\/span> 11: 278-283. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Alva_Curr.Op_.Hem2004.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Alva_Curr.Op.Hem(2004)<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L.<\/strong>, Luque, A. and Lee, N.. 2004. Thrombospondin modules in Angiogenesis. <span class=\"italics\"> Int. Journal of Biochemistry and Cell Biol<\/span> 36: 1070-1078. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/IJBCB_36.702004.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">IJBCB_36.70(2004)<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>.. 2004. Angiogenesis: novel and basic science insights and human therapy. Keystone Symposium \u2013 <span class=\"italics\"> IDrugs<\/span> 7: 111-113. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/IDrugs_KeystoneSymp2004.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">IDrugs_KeystoneSymp(2004)<\/a><\/p>\n<p>Fiala, M., Murphy, T., MacDougall, J., Yang, W., Luque, A., <strong>Iruela-Arispe, L<\/strong>., Cashman, J., Buga, G., Byrns, R.E., Barbaro, G., Arthos, J.. 2004. HAART drugs induce mitochondrial damage and intercellular gaps and gp120 causes apoptosis.<span class=\"italics\"> Cardiovasc Toxicol<\/span> 4: 327-337. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Fiala_HumanaPress2004.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Fiala_HumanaPress(2004)<\/a><\/p>\n<p>Calzada, M.J., Zhou, L., Sipes, J.M., Zhang, J., Krutzsch, H.C., <strong>Iruela-Arispe M.L<\/strong>., Annis, D.S., Mosher, D.F., Roberts, D.D.. 2004. <a href=\"http:\/\/circres.ahajournals.org\/content\/94\/4\/462.long\" target=\"_blank\" rel=\"noopener noreferrer\">Alpha4 Beta1 Integrin Mediates Selective Endothelial Cell Responses to Thrombospondins 1 and 2 In Vitro and Modulates Angiogenesis In Vivo<\/a>. <span class=\"italics\"> Circ Res<\/span> 94: 462-470.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2003\"><\/a><\/p>\n<h4><a id=\"2003\"><\/a>2003<\/h4>\n<p>Ellwood-Yen K, Graeber TG, Wongvipat J, <strong>Iruela-Arispe ML<\/strong>, Zhang J, Matusik R, Thomas GV, Sawyers CL. 2003. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. <span class=\"italics\">Cancer Cell<\/span> 4: 223-238. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/ElwoodYen.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">ElwoodYen<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Carpizo, D., Luque, A.. 2003. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1749-6632.2003.tb03221.x\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">ADAMTS1: a matrix metalloprotease with angioinhibitory properties<\/a>. <span class=\"italics\"> Ann N Y Acad Sci<\/span> 995: 183-190.<\/p>\n<p>Jilani SM, Murphy TJ, Thai SN, Eichmann A, Alva JA, <strong>Iruela-Arispe ML<\/strong>. 2003. <a href=\"http:\/\/jhc.sagepub.com\/content\/51\/5\/597.full.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Selective binding of lectins to embryonic chicken vasculature<\/a>. <span class=\"italics\">J Histochem Cytochem<\/span> 51: 597-604.<\/p>\n<p>Luque, A., Carpizo, D.R., <strong>Iruela-Arispe, M.L.<\/strong> 2003. ADAMTS1\/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165. J Biol Chem. 278:23656-665. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Luque_Jbc_2782003.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Luque_Jbc_278(2003)<\/a><\/p>\n<p><a class=\"mwm-aal-item\" name=\"2002\"><\/a><\/p>\n<h4><a id=\"2002\"><\/a>2002<\/h4>\n<p>Park H.J., Kong D., <strong>Iruela-Arispe M.L<\/strong>., Begley U, Tang D, Galper J.B.. 2002. <a href=\"http:\/\/circres.ahajournals.org\/content\/91\/2\/143.long\" target=\"_blank\" rel=\"noopener noreferrer\">3-hydroxy-3methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA<\/a>. <span class=\"italics\"> Circ Res<\/span> 91: 143-150.<\/p>\n<p>Gaspar, J., Thai, S., Voland, C., Dube, A., Libermann, T.A., <strong>Iruela-Arispe, M.L<\/strong>. and Oettgen, P.. 2002. <a href=\"http:\/\/atvb.ahajournals.org\/content\/22\/7\/1106.long\" target=\"_blank\" rel=\"noopener noreferrer\">Opposing functions of the Ets factors NERF and ELF-1 in the regulation of the Tie genes during chicken blood vessel development<\/a>. <span class=\"italics\"> Art. Throm. and Vasc. Biol<\/span> 22: 1106-1112.<\/p>\n<p>Adams, J.Y., Johnson, M., Sato, M., Berger, F., Gambhir, S.S., Carey, M., <strong>Iruela-Arispe, M.L<\/strong>. and Lily, Wu. 2002. <a href=\"http:\/\/www.nature.com\/nm\/journal\/v8\/n8\/pdf\/nm743.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging<\/a>. <span class=\"italics\"> Nature Med<\/span> 8: 891-897.<\/p>\n<p>Thai, S.N.M. and <strong>Iruela-Arispe, M.L<\/strong>.. 2002. <a href=\"http:\/\/ac.els-cdn.com\/S0925477302001156\/1-s2.0-S0925477302001156-main.pdf?_tid=3429f8ea-7cf6-11e5-b488-00000aab0f6c&amp;acdnat=1445983438_a90abb429e7b7caa855eeba058238bf7\" target=\"_blank\" rel=\"noopener noreferrer\">Expression of ADAMTS1 during murine developme<\/a><a href=\"http:\/\/ac.els-cdn.com\/S0925477302001156\/1-s2.0-S0925477302001156-main.pdf?_tid=3429f8ea-7cf6-11e5-b488-00000aab0f6c&amp;acdnat=1445983438_a90abb429e7b7caa855eeba058238bf7\" target=\"_blank\" rel=\"noopener noreferrer\">ac.els-cdn.com\/\u2026\/1-s2.0-S0925477302001156-main.pdf<\/a><a href=\"http:\/\/ac.els-cdn.com\/S0925477302001156\/1-s2.0-S0925477302001156-main.pdf?_tid=3429f8ea-7cf6-11e5-b488-00000aab0f6c&amp;acdnat=1445983438_a90abb429e7b7caa855eeba058238bf7\" target=\"_blank\" rel=\"noopener noreferrer\">nt<\/a>. <span class=\"italics\"> Mechanisms of Development<\/span> 115: 181-185.<\/p>\n<p>Rogriguez-Manzaneque, J.C., Westling, J., Thai, S.N., Luque, A., Knauper, V., Murphy, G., Sandy, J.D., and <strong>Iruela-Arispe, M.L.<\/strong>. 2002. <a href=\"http:\/\/ac.els-cdn.com\/S0006291X02002541\/1-s2.0-S0006291X02002541-main.pdf?_tid=810d5fc6-7cf6-11e5-bbce-00000aab0f01&amp;acdnat=1445983567_eb85466098b12a6d8ae5043f157c6e4f\" target=\"_blank\" rel=\"noopener noreferrer\">ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors<\/a>.<span class=\"italics\"> Biochem. and Biophys. Res. Comm<\/span> 293: 501-508.<\/p>\n<p>Murayama, Y., Vinuela, F., Tateshima, S., Gonzalez, N.R., Song, J.K., Mahdavieh, H., <strong>Iruela-Arispe, M.L<\/strong>.. 2002. <a href=\"http:\/\/stroke.ahajournals.org\/content\/33\/4\/1120.long\" target=\"_blank\" rel=\"noopener noreferrer\">Cellular responses of bioabsorbable polymeric material and Guglielmi detachable coil in experimental aneurysms<\/a>. <span class=\"italics\"> Stroke<\/span> 33: 1120-1128.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2001\"><\/a><\/p>\n<h4><a id=\"2001\"><\/a>2001<\/h4>\n<p>Rodriguez-Manzaneque, J.C., Lane, T.F., Ortega, M.A., Hynes, R.O., Lawler, J., and <strong>Iruela-Arispe, M.L<\/strong>.. 2001. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC60080\/pdf\/pq012485.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor<\/a>. <span class=\"italics\"> PNAS<\/span> 98: 12485-12490. PMCID: PMC60080<\/p>\n<p>Villa, N., Walker, L., Lindsell, C.E., Gasson, J., <strong>Iruela-Arispe, M.L.<\/strong> and Weinmaster, G.. 2001. <a href=\"http:\/\/ac.els-cdn.com\/S0925477301004695\/1-s2.0-S0925477301004695-main.pdf?_tid=61051598-7d82-11e5-9fa1-00000aacb35d&amp;acdnat=1446043643_0f9d92847070839366029dfe07708b49\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels<\/a>. <span class=\"italics\"> Mechanisms of Development<\/span> 108: 161-164.<\/p>\n<p>Augustin, H.G., <strong>Iruela-Arispe, M.L.<\/strong>, Rogers, P., and Smith, S.. 2001. Vascular Morphogenesis in the Female Reproductive System. <span class=\"italics\"> Springer-Birkhaeuser, New York<\/span> : 161-164.<\/p>\n<p>Saaristo, A., Karkkainen, M.J., Alitalo, K., Montesano, R., <strong>Iruela-Arispe, M.L.<\/strong>, Pepper, M.S.. 2001. Growth factor regulation of physiological angiogenesis in the mammary gland <span class=\"italics\"> Chapter in: Vascular Morphogenesis in the Female Reproductive System<\/span> : 25-40. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Saaristo_et_al_2001.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Saaristo_et_al_2001<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Ortega, M.A., Oikemus, S. and Pepper, M.S.. 2001. Vascular morphogenesis in the mammary gland \u2013 introduction and overview <span class=\"italics\"> Vascular Morphogenesis in the Female Reproductive System<\/span> : 3-24. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Arispe_et_al_2001.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Arispe_et_al_2001<\/a><\/p>\n<p>Sandy, J.D., Westling, J., Kenagy, R.D., <strong>Iruela-Arispe, M.L<\/strong>., Verscharen, C., Rodriguez-Manzaneque, J.C., Zimmerman, D., Lemire, J.M., Fischer, J.W., Wight, T.N and Clowes, A.W.. 2001. <a href=\"http:\/\/www.jbc.org\/content\/276\/16\/13372.long\" target=\"_blank\" rel=\"noopener noreferrer\">Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site which is cleaved by recombinant ADAMTS-1 and ADAMTS-4<\/a>. <span class=\"italics\"> J. Biol. Chem<\/span> 276: 13372-13378.<\/p>\n<p>Dube, A., Thai, S., Gaspar, J., Rudders, S., Libermann, T.A., <strong>Iruela-Arispe, M.L<\/strong>., and Oettgen, P.. 2001. <a href=\"http:\/\/circres.ahajournals.org\/content\/88\/2\/237.long\" target=\"_blank\" rel=\"noopener noreferrer\">ELF-1 is a transcriptional regulator of the Tie-2 gene during vascular development<\/a>. <span class=\"italics\"> Circ. Res<\/span> 88: 237-244.<\/p>\n<p>Graubert, M.D., Ortega, M.A., Kessel, B., Mortola, J.F. and <strong>Iruela-Arispe, M.L<\/strong>.. 2001. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1891924\/pdf\/2604.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular repair after menstruation involves regulation of vascular endothelial growth factor-receptor phosphorylation by sFLT-1<\/a>. <span class=\"italics\"> Am. J. Pathol<\/span> 158: 1399-1410. PMCID: PMC1891924<\/p>\n<p><a class=\"mwm-aal-item\" name=\"2000\"><\/a><\/p>\n<h4><a id=\"2000\"><\/a>2000<\/h4>\n<p>Carpizo, D. and <strong>Iruela-Arispe, M.L<\/strong>.. 2000. Endogenous regulators of angiogenesis \u2013 Emphasis on proteins with thrombospondin \u2013 type I motifs. <span class=\"italics\"> Cancer and Metastasis Reviews<\/span> 19: 159-165. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Carpizo_CanMet_192000.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Carpizo_CanMet_19(2000)<\/a><\/p>\n<p>Pal, S., <strong>Iruela-Arispe, M.L<\/strong>., Harvey, V.S., Zeng, H., Nagy, J.A., Dvorak, H.F. and Mukhopadhyay, D.. 2000. <a href=\"http:\/\/ac.els-cdn.com\/S0026286200922465\/1-s2.0-S0026286200922465-main.pdf?_tid=1b457e34-7d88-11e5-87f0-00000aacb360&amp;acdnat=1446046103_e575c6d4ef4befe23aca165650eebb40\" target=\"_blank\" rel=\"noopener noreferrer\">Retinoic acid selectively inhibits the vascular permeabilizing effect of VPF\/VEGF, an early step in the angiogenic cascad<\/a>e. <span class=\"italics\"> Microvasc. Res<\/span> 60: 112-120.<\/p>\n<p>Rodriguez-Manzaneque, J.C., Milchanowski, A.B., Dufour, E.K., Leduc, R., and <strong>Iruela-Arispe, M.L<\/strong>.. 2000. <a href=\"http:\/\/www.jbc.org\/content\/275\/43\/33471.long\" target=\"_blank\" rel=\"noopener noreferrer\">Characterization of Meth-1\/Adamts-1 processing reveals two distinct active forms<\/a>. <span class=\"italics\"> J. Biol. Chem<\/span> 275: 33471-33479.<\/p>\n<p>Streit, M., Valesco, P., Riccardi, L., Spencer, L., Brown, L.F., Janes, L., Lange-Asschenfeldt, B. ,Yano, K., Hawighorst, T., <strong>Iruela-Arispe, M.L<\/strong>., Detmar, M.. 2000. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC313956\/pdf\/cdd339.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice<\/a>. <span class=\"italics\"> The EMBO Journal<\/span> 19: 3272-3282 .<\/p>\n<p>Pepper, M.S., Baetens, D., Mandroita, S.J., Di Sanza, C., Oikemus, S., Lane, T.F., Soriano, J.V., Orci, L., Montesano, R., <strong>Iruela-Arispe, M.L<\/strong>.. 2000. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/1097-0177%28200007%29218:3%3C507::AID-DVDY1012%3E3.0.CO;2-5\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Regulation of VEGF and VEGF receptor expression in rodent mammary gland during pregnancy, lactation and involution.<\/a> <span class=\"italics\"> Dev. Dynamics<\/span> 218: 507-524.<\/p>\n<p>Lee S.W., Reimer, C.L., Fang, L., <strong>Iruela-Arispe, M.L<\/strong>. and Aaronson, S.A.. 2000. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC85355\/\" target=\"_blank\" rel=\"noopener noreferrer\">Overexpression of kinase-associated phosphatase (KAP) in Breast and Prostate Cancer Inhibition of the transformed phenotype by antisense KAP Expression<\/a>.<span class=\"italics\"> Molec. &amp; Cell. Biol<\/span> 20: 1723-1732. PMCID: PMC85355<\/p>\n<p>Chandrasekaran, L., He, Z.C., Al-Barazi, H., Krutzch, H.C., <strong>Iruela-Arispe, M.L<\/strong>., and Roberts, D.D.. 2000. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC14963\/pdf\/mk002885.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Cell contact-dependent activation of a 3b1 integrin modulates endothelial cell responses to thrombospondin-1<\/a>. <span class=\"italics\"> Mol. Biol. Cell<\/span> 11: 2885-2900. PMCID: PMC14963<\/p>\n<p>Rodriguez-Manzaneque, J.C., Graubert, M., and <strong>Iruela-Arispe, M.L.<\/strong>. 2000. Endothelial cell dysfunction following prolonged activation of progesterone receptor. <span class=\"italics\"> Human Reproduction<\/span> 15: 39-47. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Juan_hum_rep_152000.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Juan_hum_rep_15(2000)<\/a><\/p>\n<p><a class=\"mwm-aal-item\" name=\"1990s\"><\/a><\/p>\n<h4><a id=\"1990s\"><\/a>1990s<\/h4>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Ortega, M.A., and Vazquez, F.. 1999. Antiangiogenic Function of Thrombospondin-1. <span class=\"italics\"> Angiogenesis in Health and Disease: Basic Mechanisms and Clinical Applications<\/span> : 349-357. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/antiangiogenic1999.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">antiangiogenic1999<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Vazquez, F., and Ortega, M.A.. 1999. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1749-6632.1999.tb09400.x\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Anti-angiogenic domains shared by thrombospondins and metallospondins, a new family of angiogenic inhibitors<\/a>. <span class=\"italics\"> Ann. N.Y. Acad. Sci<\/span> 886: 58-66.<\/p>\n<p><strong>Iruela-Arispe, M.L.<\/strong>, Lombardo, M., Krutzsch, H.C., Lawler, J., and Roberts, D.D.. 1999. <a href=\"http:\/\/circ.ahajournals.org\/content\/100\/13\/1423.long\" target=\"_blank\" rel=\"noopener noreferrer\">Inhibition of angiogenesis by thrombospondin-1 is mediated by two independent regions within the type1 repeats<\/a>. <span class=\"italics\"> Circulation<\/span> 100: 1423-1431.<\/p>\n<p>Wu. H., Lee, S.H., Jing Gao, Xin Liu, and <strong>Iruela-Arispe, M.L<\/strong>.. 1999. <a href=\"http:\/\/dev.biologists.org\/content\/126\/16\/3597.long\" target=\"_blank\" rel=\"noopener noreferrer\">Inactivation of erythropoetin leads to defects in cardiac morphogenesis<\/a>. <span class=\"italics\"> Development<\/span> 126: 3597-3605.<\/p>\n<p>Vazquez, F., Hasting, G., Ortega, M.A., Lane, T.F., Oikemus, S., Lombardo, M., and <strong>Iruela-Arispe, M.L<\/strong>.. 1999. <a href=\"http:\/\/www.jbc.org\/content\/274\/33\/23349.long\" target=\"_blank\" rel=\"noopener noreferrer\">METH1 a human ortholog of ADAMTS, and METH2 are members of a new family of proteins with angio-inhibitory activity<\/a>. <span class=\"italics\"> J. Bio. Chem<\/span> 274: 23349-23357.<\/p>\n<p>Zhai, Y., Yu, L., <strong>Iruela- Arispe, L<\/strong>., Huang, W.Q., Wang, Z., Hayes, A.J., Lu, J., Jaing, G., Rojas, L., Lippman, M.E., Ni, J., Yu, G.L., and Li, L.Y.. 1999. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/%28SICI%291097-0215%2819990702%2982:1%3C131::AID-IJC22%3E3.0.CO;2-O\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Inhibition of angiogenesis and breast cancer xenograft tumor by VEGI, a novel cytokine of the TNF superfamily<\/a>. <span class=\"italics\"> Int. J. Cancer<\/span> 82: 131-136.<\/p>\n<p>Brown, L.F., Guidi, A.J., Schnitt, S.J., Van De Water, L., <strong>Iruela- Arispe, M.L<\/strong>., Yeu, T.K., Tognassi, K., Dvorak, H.F.. 1999. <a href=\"http:\/\/clincancerres.aacrjournals.org\/content\/5\/5\/1041.long\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breas<\/a>t.<span class=\"italics\"> Clin. Cancer Res<\/span> 5: 1041-1056.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Rodriguez- Manzaneque, and Abu-Jawdeh, G.. 1999. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1549-8719.1999.tb00095.x\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Endometrical endothelial cells express estrogen and progesterone receptors and exhibit a tissue specific response to antiogenic growth factors<\/a>.<span class=\"italics\"> Microcirculation<\/span> 6: 127-140.<\/p>\n<p>Dhanabal, M., Ramchandran, R., Volk, R., Stillman, I.E., Lombardo, M., <strong>Iruela-Arispe, M.L<\/strong>., Simons, M., and Sukhatme, V.P.. 1999. <a href=\"http:\/\/cancerres.aacrjournals.org\/content\/59\/1\/189.long\" target=\"_blank\" rel=\"noopener noreferrer\">Endostatin: yeast production, mutants, and anti-tumor effect in renal cell carcinoma<\/a>. <span class=\"italics\"> Cancer Res<\/span> 59: 189-197.<\/p>\n<p>Vazquez, F., Rodriguez-Manzaneque, J.C., Lydon, J.P., Edwards, D.P., O\u2019Malley B.W., and <strong>Iruela-Arispe, M.L<\/strong>.. 1999. <a href=\"http:\/\/www.jbc.org\/content\/274\/4\/2185.long\" target=\"_blank\" rel=\"noopener noreferrer\">Progesterone regulates proliferation of endothelial cells<\/a>.<span class=\"italics\"> J. Biol. Chem<\/span> 274: 2185-2192.<\/p>\n<p>Lee, S.H.,Hungerford, J.E., Little, C.D. and <strong>Iruela-Arispe, M.L<\/strong>.. 1997. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/%28SICI%291097-0177%28199708%29209:4%3C342::AID-AJA2%3E3.0.CO;2-I\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Proliferation and differentiation of smooth muscle cell precursors occurs simultaneously during the development of the vessel wall<\/a>. <span class=\"italics\"> Dev. Dyn<\/span> 209: 342-352.<\/p>\n<p><strong>Iruela-Arispe, M.L.<\/strong> and Dvorak, H.F.. 1997. Angiogenesis: A dynamic balance of stimulator and inhibitors. <span class=\"italics\"> Thromb. Haem<\/span> 78: 672-677. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Thromb.Haem7816721997.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Thromb.Haem78(1)672(1997)<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>.. 1997. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC508031\/pdf\/992057.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Normal placentation: A tale that requires an epithelial-to-endothelial conversion<\/a>. <span class=\"italics\"> J. Clin.Invest<\/span> 99: 2057-2058.<\/p>\n<p>Brown, L.F., Demar, M., Tognazzi, K., Abu-Jawdeh., G. and <strong>Iruela-Arispe, M.L<\/strong>.. 1997. Uterine smooth muscle cells express functional receptors (flt-1 and KDR) for vascular permeability factor (vascular endothelial growth factor). <span class=\"italics\"> Lab. Invest<\/span> 76: 245-255. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Brown_Lab-Invest_761997f.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Brown_Lab Invest_76(1997)f<\/a><\/p>\n<p>Luther, T., Flossel, C., Mackman, N., Bierhaus, A., Kasper, M., Albrecht, S., Sage, E.H., <strong>Iruela-Arispe, L<\/strong>., Grossmann, H., Strohlein, A., Zhang, Y., Nawroth, P.P., Carmeliet, P., Loskutoff, D.J., and Mueller, M.. 1996. Tissue factor expression during human and mouse development. <span class=\"italics\"> Am. J. Pathol<\/span> 149: 101-113. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Luther_AJP_1491996.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Luther_AJP_149(1996)<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Vernon, R.B., Wu, H., Jaenish, R., and Sage, E.H.. 1996. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/%28SICI%291097-0177%28199610%29207:2%3C171::AID-AJA5%3E3.0.CO;2-E\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Type I collagen-deficient mov 13 mice do not retain SPARC in the extracellular matrix: Implications for fibroblast function<\/a>. <span class=\"italics\"> Dev. Dyn<\/span> 207: 171-183.<\/p>\n<p>Gariano, R.F., <strong>Iruela-Arispe M.L<\/strong>., Sage, E. H., and Hendrickson, A.E.. 1996. <a href=\"http:\/\/iovs.arvojournals.org\/article.aspx?articleid=2180345\" target=\"_blank\" rel=\"noopener noreferrer\">Immunohistochemical characterization of developing and mature primate retinal blood vessels<\/a>. <span class=\"italics\"> Invest. Ophthalmol. &amp; Visual Science<\/span> 37: 93-103.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Porter, P., Bornstein, P., and Sage E.H.. 1996. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC507031\/pdf\/970403.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Thrombospondin-1, an inhibitor of angiogenesis, is regulated by progesterone in human endometrium<\/a>. <span class=\"italics\"> J. Clin. Invest<\/span> 97: 403-412. PMCID: PMC507031<\/p>\n<p><strong>Iruela-Arispe, L<\/strong>., Gordon, K., Hugo, C., Duijvestijn, A. M. Claffey, K.P., Reilly, M., Couser, W. G., Alpers, C.E. and Johnson, R.J.. 1995. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1869935\/pdf\/amjpathol00048-0199.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Participation of glomerular endothelial cells in the capillary repair of glomerulonephritis<\/a>. <span class=\"italics\"> Am. J. Pathol<\/span> 147: 1715-1728. PMCID: PMC1869935<\/p>\n<p>Reed, M.J., <strong>Iruela-Arispe, M.L<\/strong>., O\u2019 Brein, E.R., Truong, T., LaBell, T., Bornstein, P., and Sage E.H.. 1995. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1870996\/pdf\/amjpathol00046-0202.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Expression of thrombospondins by endotheial cells: injury is correlated with TSP1<\/a>. <span class=\"italics\"> Am. J. Pathol<\/span> 147: 1068-1080. PMCID: PMC1870996<\/p>\n<p>Seiffert, D., <strong>Iruela-Arispe, M.L.<\/strong>, Sage, E.H., and Loskutoff, D.J.. 1995. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/aja.1002030108\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Distribution of vitronectin mRNA during murine development.<\/a> <span class=\"italics\"> Dev. Dyn<\/span> 203: 71-79.<\/p>\n<p>Vernon, R.B., Lara, S.L., Drake, C.J., <strong>Iruela-Arispe, M.L<\/strong>., Angello J.C., Little, C.D., Wight, T.N. and Sage, E.H.. 1995. <a href=\"http:\/\/download.springer.com\/static\/pdf\/646\/art%253A10.1007%252FBF02633972.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2FBF02633972&amp;token2=exp=1446058091%7Eacl=%2Fstatic%2Fpdf%2F646%2Fart%25253A10.1007%25252FBF02633972.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252FBF02633972*%7Ehmac=a37070269d38abb25a686b2de4740288bc4fc4b2c485e4fd6c7bbd81b5fb37b3\" target=\"_blank\" rel=\"noopener noreferrer\">Organized Type I collagen influences endothelial patterns during \u201cspontaneous angiogenesis in vitro\u201d: planar cultures as models of vascular development<\/a>. <span class=\"italics\"> Cell Dev. Biol<\/span> 31: 120-131.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Lane, T.F., Redmond, D., Reilly, M., Bolender, R., and Kavanaugh, T.J. and Sage E.H.. 1995. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC301191\/pdf\/mbc00072-0094.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Expression of SPARC during the development of the chorioallantoic membrane: evidence for regulated proteolysis in vivo<\/a>. <span class=\"italics\">Mol. Biol. Cell<\/span> 6: 327-343. PMCID: PMC301191<\/p>\n<p>Gariano, R.F., <strong>Iruela-Arispe, M.L<\/strong>. and Hendrickson, A.E.. 1994. <a href=\"http:\/\/iovs.arvojournals.org\/article.aspx?articleid=2179749\" target=\"_blank\" rel=\"noopener noreferrer\">Vascular Development in the primate retina: Comparison of laminar plexus formation in monkey and human.<\/a> <span class=\"italics\"> Invest. Ophtal. Vis. Sci<\/span> 35: 3442-3455.<\/p>\n<p>Lane, T.F., <strong>Iruela-Arispe, M.L<\/strong>., Johnson, R.S. and Sage, E.H.. 1994. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2120067\/pdf\/jc1254929.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">SPARC is a source of copper-binding peptides that stimulate angiogenesis<\/a>. <span class=\"italics\">J. Cell Biol<\/span> 125: 929-943. PMCID: PMC2120067<\/p>\n<p>Battegay, E. J., Rupp, J., <strong>Iruela-Arispe, M.L<\/strong>., Sage, E.H., and Pech, M.. 1994. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2120083\/pdf\/jc1254917.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGFB-receptors<\/a>. <span class=\"italics\">J. Cell Biol<\/span> 125: 917-928. PMCID: PMC2120083<\/p>\n<p><strong>Iruela-Arispe, M.L.<\/strong>,Liska, D.A., Sage, E.H. and Borenstein, P.. 1994. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/aja.1001970105\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Differential of Expression of Thrombospondin 1, 2, an 3 during Murine Development<\/a>. <span class=\"italics\"> Dev. Dyn<\/span> 197: 40-56.<\/p>\n<p>Bassuk, J.A., <strong>Iruela-Arispe, M.L.<\/strong>, Lane, T.F., Benson, J. M., Berg, R.A., and Sage, E.H.. 1993. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1432-1033.1993.tb18358.x\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Molecular analysis of chicken embryo SPARC<\/a>. <span class=\"italics\"> Europ. J Biochem<\/span> 218: 117-127.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., and Sage, E.H.. 1993. Endothelial Cells Exhibiting Angiogenesis In vitro Proliferate in Response to TGF-B1. <span class=\"italics\"> J. Cell. Biochem<\/span> 52: 414-430. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Arispe_JCBiochem_521993.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Arispe_JCBiochem_52(1993)<\/a><\/p>\n<p>Floege, J., Johnson, R.J., Gordon, K., Yoshimura, A., Campell, C., <strong>Iruela-Arispe, M.L<\/strong>., Alpers, C.E., Couser, W.G.. 1992. Altered Glomerular Extracellular Matrix Synthesis in Experimental Membranous Nephropathy. <span class=\"italics\"> Kidney Int<\/span> 42: 573-585. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Floege_kidney.int_421992.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Floege_kidney.int_42(1992)<\/a><\/p>\n<p>Javelainen, H.T., <strong>Iruela-Arispe, M.L<\/strong>., Kinsella, M.G. Sandell, L.J., Sage, E.H., and Wight, T.N.. 1992. Expression of decorin by sprouting bovine aortic endothelial cells exhibiting angiogenesis in Vitro. <span class=\"italics\"> Exp. Cell Res<\/span> 203: 395-401. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Jarvelainen_Exp.Cell_.Res2031992.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Jarvelainen_Exp.Cell.Res203(1992)<\/a><\/p>\n<p>Sage, E.H., Lane, T.F., <strong>Iruela-Arispe, M.L.<\/strong> and Funk, S.E.. 1992. A Protein that Modulates Cell Cycle and Cell-matrix Interactions. <span class=\"italics\"> Proc. Forth Int\u2019l Conf. Chem. Biol. Mineraliz. Tiss<\/span> : 235-242. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Sage_235-421992.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Sage_235-42(1992)<\/a><\/p>\n<p>Lane, T., <strong>Iruela-Arispe, M.L.<\/strong> and Sage, E.H.. 1992. <a href=\"http:\/\/www.jbc.org\/content\/267\/23\/16736.long\" target=\"_blank\" rel=\"noopener noreferrer\">Regulation of Gene Expression by SPARC during Angiogenesis in vitro: Changes in Fibronectin, Thrombospondin- 1, and Plasminogen Activator Inhibitor- 1<\/a>. <span class=\"italics\"> J. Bio. Chem<\/span> 267: 16736-16745.<\/p>\n<p>Vernon R.B., Angello, J.C., <strong>Iruela-Arispe, M.L<\/strong>., Lane, T.F., and Sage E.H.. 1992. Reorganization of Basement Membrane Matrices by Cellular Traction Promotes the Formation of Cellular Networks in vitro. <span class=\"italics\">Lab. Invest<\/span> 66: 536-547. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Vernon_LabInvest_661992.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Vernon_LabInvest_66(1992)<\/a><\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Chun, L., and Sage, E. H.. 1992. Structure and Biology of Type VIII Collagen. <span class=\"italics\"> Trends Glycosci. Glycotechnol<\/span> 4: 188-199. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Arispe_Glycosci.Glycotech_41992.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Arispe_Glycosci.Glycotech_4(1992)<\/a><\/p>\n<p>Raines, E.W., Lane, T., <strong>Iruela-Arispe, M.L<\/strong>.,Ross, R., and Sage, E.H.. 1992. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC48433\/pdf\/pnas01078-0141.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">The Extracellular Glycoprotein SPARC Interacts with Platelet-derived Growth Factor (PDGF)-AB and BB and Inhibits Binding of PDGF to its Receptors<\/a>. <span class=\"italics\"> Proc. Natl.Acad. Sci<\/span> 89: 1281-1285. PMCID: PMC48433<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Diglio, C.A. and Sage, E.H.. 1991. <a href=\"http:\/\/atvb.ahajournals.org\/content\/11\/4\/805.long\" target=\"_blank\" rel=\"noopener noreferrer\">Modulation of Extracellular Matrix Proteins by Endothelial Cells undergoing Angiogenesis in vitro<\/a>. <span class=\"italics\"> Arterioscler. Thromb<\/span> 11: 805-815.<\/p>\n<p>Fouser, L.,<strong> Iruela-Arispe, M.L<\/strong>., Borstein, P., and Sage, E.H.. 1991. <a href=\"http:\/\/www.jbc.org\/content\/266\/27\/18345.long\" target=\"_blank\" rel=\"noopener noreferrer\">Transcriptional Activity of the alpha 1(I)-Collagen Promoter in Endothelial Cells is Correlated with the Formation of Capillary-like Structures by Endothelial Cells in Vitro<\/a>. <span class=\"italics\"> J. Biol. Chem<\/span> 266: 18345-18351.<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., Bornstein, P., and Sage, H.. 1991. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC51800\/pdf\/pnas01061-0472.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Thrombospondin Exerts an Antiangiogenic Effect on Tube Formation by Endothelial Cells in vitro<\/a>. <span class=\"italics\"> Proc. Natl. Acad. Sci<\/span> 88: 5026-5030. PMCID: PMC51800<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>., and Sage, H.. 1991. <a href=\"http:\/\/ac.els-cdn.com\/001216069190483J\/1-s2.0-001216069190483J-main.pdf?_tid=8dfe76ea-7db2-11e5-859d-00000aab0f01&amp;acdnat=1446064334_c1798893f9a52c10a5c128a6c8511ade\" target=\"_blank\" rel=\"noopener noreferrer\">Expression of Type VIII Collagen during Morphogenesis of the Chicken and Mouse Hear<\/a>t. <span class=\"italics\">Dev. Biol<\/span> 144: 107-118.<\/p>\n<p>Paulus, W., Sage, H., Liszka, U., <strong>Iruela-Arispe, M.L<\/strong>. and Jellinger, K.. 1991. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1971869\/pdf\/brjcancer00211-0043.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Increased levels of type VIII collagen in human brain tumours compared to normal brain tissue and non-neoplastic cerebral disorders<\/a>. <span class=\"italics\"> Brit. J. Cancer<\/span> 63: 367-371. PMCID: PMC1971869<\/p>\n<p><strong>Iruela-Arispe, M.L<\/strong>. Hasselaar, P., Sage, H.. 1990. Differential Expression of Extracellular Proteins is correlated with Angiogenesis in vitro. <span class=\"italics\"> Lab. Invest<\/span> 64: 174-186. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Arispe_lab.inv_641991.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Arispe_lab.inv_64(1991)<\/a><\/p>\n<p>Sage, H. and <strong>Iruela-Arispe, M.L<\/strong>.. 1990. <a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1749-6632.1990.tb17914.x\/epdf\" target=\"_blank\" rel=\"noopener noreferrer\">Type VIII Collagen in Murine Development<\/a>. Association with Capillary Formation in vitro. <span class=\"italics\"> Structure, Molecular Biology and Pathology of Collagen<\/span> 580: 17-31.<\/p>\n<p><a class=\"mwm-aal-item\" name=\"1980s\"><\/a><\/p>\n<h4><a id=\"1980s\"><\/a>1980s<\/h4>\n<p>Sage, H., Vernon, R.D., Decker, J., Funk, S., and <strong>Iruela-Arispe, M.L<\/strong>.. 1989. <a href=\"http:\/\/jhc.sagepub.com\/content\/37\/6\/819.long\" target=\"_blank\" rel=\"noopener noreferrer\">Distribution of the Calcium-binding Protein SPARC in Tissues of Embryonic and Adult Mice<\/a>.<span class=\"italics\"> J. Histochem. Cytochem<\/span> 37: 819-829.<\/p>\n<p>Chow, M., Boyd, C.D., <strong>Iruela-Arispe, M.L<\/strong>., Wrenn, D.S., Mecham, R., and Sage, H.. 1989. Characterization of Elastin Protein and mRNA from Salmonid Fish (Oncorhynchus kisutch).<span class=\"italics\"> Comp. Biochem. Physiol<\/span> 93: 835-845. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/Chow_Comp.Bioch_.Phys_93B1989.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Chow_Comp.Bioch.Phys_93B(1989)<\/a><\/p>\n<p>Cotta-Pereira, G. and <strong>Iruela-Arispe, M.L<\/strong>.. 1989. Extracellular matrix: Functional significance of oxytalan, elaunin and elastic fibers. <span class=\"italics\"> Cells and Tissues: A Three Dimensional Approach by Modern Techniques in Microscopy<\/span> : 61-67. <a href=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/cells_tissues1989.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">cells_tissues(1989)<\/a><\/p>\n<p>Cotta-Pereira, G. and <strong>Iruela-Arispe, M.L<\/strong>.. 1988. Extracurricular Matrix: Functional Significance of Oxytalan, Elaunin and Elastic Fibers. <span class=\"italics\"> Quaderni di Anatomia Practica<\/span> 295:101-7.<\/p>\n<\/div>\n<\/article>\n<\/div>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-1jhp6-8514a544d048a86d8471c2c60f06f12b\">\n.flex_column.av-1jhp6-8514a544d048a86d8471c2c60f06f12b{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\nbackground-color:#cccccc;\n}\n<\/style>\n<div  class='flex_column av-1jhp6-8514a544d048a86d8471c2c60f06f12b av_one_full  avia-builder-el-6  el_after_av_one_full  avia-builder-el-last  first flex_column_div av-zero-column-padding  column-top-margin'     ><div  class='avia-builder-widget-area clearfix  avia-builder-el-7  avia-builder-el-no-sibling '><div id=\"text-6\" class=\"widget clearfix widget_text\">\t\t\t<div class=\"textwidget\"><div style=\"background: #ccc; padding: 8px;height:71px !important; \"><a href=\"https:\/\/www.ucla.edu\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-content\/uploads\/sites\/126\/2017\/05\/UCLA_logo_blue.png\" style=\"height:65px !important;float:right !important;\"><\/a><\/div><\/div>\n\t\t<\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-18","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/pages\/18","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/comments?post=18"}],"version-history":[{"count":38,"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/pages\/18\/revisions"}],"predecessor-version":[{"id":1155,"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/pages\/18\/revisions\/1155"}],"wp:attachment":[{"href":"https:\/\/sites.lifesci.ucla.edu\/mcdb-arispe\/wp-json\/wp\/v2\/media?parent=18"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}