{"id":80,"date":"2013-12-16T10:36:18","date_gmt":"2013-12-16T10:36:18","guid":{"rendered":"http:\/\/braybrookgroup.wordpress.com\/?page_id=5"},"modified":"2025-03-27T13:24:46","modified_gmt":"2025-03-27T20:24:46","slug":"home","status":"publish","type":"page","link":"https:\/\/sites.lifesci.ucla.edu\/mcdb-braybrook\/","title":{"rendered":"Welcome!"},"content":{"rendered":"

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How do organisms get their shapes?<\/span><\/h4>\n

Our lab is interested in understanding the mech<\/span>anisms and mech<\/span>anics of morpho<\/span>genesis in brown macroalgae<\/span> and plants<\/span>.<\/p>\n

While these two groups of eukaryotes evolved separately, they have strikingly similar features central to our research: complex developmental patterning mechanisms,<\/span>\u00a0functionally analogous organs,<\/span>\u00a0& polysaccharide-based cell walls<\/span>.<\/p>\n

Current Research Themes in Our Lab<\/strong><\/h4>\n

Cell expansion, cell shape, and morphology in plants.<\/span> The control of plant cell expansion on cell, tissue, and organ levels is a key process in growth and development, with impacts on organismal form & function. We examine such processes by centering the mechanical role of the cell wall in regulating cell expansion and shape; our major study system in the Arabidopsis<\/em> hypocotyl. What components of the cell wall permit and restrict growth? What organ and tissue-level hormonal controls regulate cell expansion, via the wall? How do changes in the execution of cell expansion and cell shape impact organismal function? Find out more here<\/a>!<\/p>\n

Morphology, Growth, & Development in Brown Macroalgae. <\/span>We are curious about brown macroalgae here in California, focusing on the orders Fucales and Laminarales (kelp). Our lab is currently interested in three major areas: branching patterns\/phyllotxais, embryo development, and environmental impacts on growth. Learn more about current projects here<\/a>!<\/span><\/span><\/p>\n\n\n\n
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A herbarium specimine of Anthophycus longifolius exhibitng alternate, planar, branching.<\/figcaption><\/figure><\/td>\n
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Young embryos of Feather Boa Kelp (Egregia menziesii) imaged by confocal microscopy. The embryos (juvenile sporophytes or recruits) are still attactched to the parent megagametophyte in the center (turquoise only). Pink indicates chloroplast autofluorescence.<\/figcaption><\/figure><\/td>\n
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A giant kelp (Macrocystis pyrifera) megagametophyte imaged by confocal microscopy after cultivation in simulated ocean warming conditions.<\/figcaption><\/figure><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

The brown algal cell wall and its role in growth, development, and survival. \u00a0The cell wall plays a mechanical role in regulating organismal growth and<\/em> it is the organism’s major interface with the external biotic and abiotic environment. The same polysaccharides in the wall important for growth & development also play roles in the algal microbiome and even heavy metal tolerance. Check out our current projects here<\/a>!<\/span><\/span><\/p>\n\n\n\n
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A culture plate of microbes grown after swabbing an intertidal brown macroalgae, Fucus distichus.<\/figcaption><\/figure><\/td>\n
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A California kelp forest, where our field work happens and where heavy metals interact with kelp.<\/figcaption><\/figure><\/td>\n
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Methods & tool development for brown macroalgae.<\/span> Brown macroalgae are tough, and they don’t make molecular biology easy – but we think they are worth careful, patient, persistent effort. Together with a small-but-mighty research community we are optimizing, adapting, and developing methods and tools needed for modern molecular biology in brown algae. Examples in our lab include: quality, purpose-driven, nucleic acid extraction methods; advanced imaging methods with confocal & AFM; RNAseq for de novo<\/em> transcriptome assembly & gene expression analyses; laser capture microdissection; and RNAi and CRISPR-gene editing.\u00a0<\/span><\/p>\n

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Want to know more about cell walls? Check out the iBiology video below! Go to iBiology<\/a> to see more on plant and algal cell walls!<\/p>\n