Publications

Ardehali, Reza

• Konstantina-Ioanna Sereti, Ngoc B. Nguyen, Paniz Kamran, Peng Zhao, Sara Ranjbarvaziri, Shuin Park, Shan Sabri, James L. Engel, Kevin Sung, Rajan P. Kulkarni, Yichen Ding, Tzung K. Hsiai1, Kathrin Plath, Jason Ernst, Debashis Sahoo, Hanna K.A. Mikkola, M. Luisa Iruela-Arispe & Reza Ardehali (2018). Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nature Communications, 9:754 https://www.nature.com/articles/s41467-018-02891-z.pdf

 

• Park, S., Ranjbarvaziri, S., Lay, FD., Zhao, P., Miller, MJ., Dhaliwal, JS., Huertas-Vazquez, A., Wu, X., Qiao, R., Soffer, JM., Rau, C., Wang, Y., Mikkola, HKA., Lusis, AJ., Ardehali, R. (2018) Genetic regulation of fibroblast activation and proliferation in cardiac fibrosis. Circulation. 138:1224–1235. https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.118.035420

Banerjee, Utpal

• Cho B, Spratford CM, Yoon S, Cha N, Banerjee U, Shim J. Systemic control of immune cell development by integrated carbon dioxide and hypoxia chemosensation in Drosophila. Nature Communications, 9(1):2679. 2018 Jul 11. http://dx.doi.org/10.1038/s41467-018-04990-3

 

• Nagaraj R, Sharpley MS, Yonggang Zhou Y, Chi F, Braas D, Kim R, Clark AT, Banerjee U. Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation. Cell, 168(1-2):210-223. 2017 Jan. https://linkinghub.elsevier.com/retrieve/pii/S0092-8674(16)31742-1

 

• Wang CW, Purkayastha A, Jones KT, Thaker SK, Banerjee U. In vivo genetic dissection of tumor growth and the Warburg effect. eLife. 2016 Sep 1. https://doi.org/10.7554/eLife.18126

 

• Mondal BC, Shim J, Evans CJ, Banerjee U. Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors. eLife. 2014 Sep 8. https://doi.org/10.7554/eLife.03626

 

• Shim J, Mukherjee T, Mondal BC, Liu T, Young GC, Wijewarnasuriya DP, Banerjee U. Olfactory control of blood progenitor maintenance. Cell. 2013 Nov 21;155(5):1141-53. https://linkinghub.elsevier.com/retrieve/pii/S0092-8674(13)01350-0

 

• Shim J, Gururaja-Rao S, Banerjee U. Nutritional regulation of stem and progenitor cells in Drosophila. Development. 2013 Dec;140(23):4647-56. http://dev.biologists.org/cgi/pmidlookup?view=long&pmid=24255094

 

• Grigorian M, Liu T, Banerjee U, Hartenstein V. The proteoglycan Trol controls the architecture of the extracellular matrix and balances proliferation and differentiation of blood progenitors in the Drosophila lymph gland. Developmental Biology. 2013 Mar 16. https://linkinghub.elsevier.com/retrieve/pii/S0012-1606(13)00136-X

Black, Douglas L.

• Vuong CK, Wei W, Lee JA, Lin CH, Damianov A, de la Torre-Ubieta L, Halabi R, Otis KO, Martin KC, O’Dell TJ, Black DL. Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1. Neuron. 2018 Apr 4;98(1):127-141.e7. doi: 10.1016/j.neuron.2018.03.008. PubMed PMID: 29621484; PubMed Central PMCID: PMC5890944. https://www.ncbi.nlm.nih.gov/pubmed/29621484

Butler, Samantha

• Varadarajan, S.G., Kong, J. H., Phan, K.D., Kao, T.-J., Panaitof, S.G., Cardin, J., Eltzschig, H., Kania A., Novitch B.G. and S.J. Butler (2017). Netrin1 produced by neural progenitors, not floor plate cells, is required for axon guidance in the spinal cord. Neuron, 94:790-799DOI:https://doi.org/10.1016/j.neuron.2017.03.007

 

• Varadarajan, S.G. and S.J. Butler (2017). Netrin1 establishes multiple boundaries for axon growth in the developing spinal cord. Developmental Biology, 430: 177-187DOI:http://dx.doi.org/10.1016/j.ydbio.2017.08.001

 

• Andrews, M.G., del Castillo, L.M., Ochoa-Bolton, E., Yamauchi, K., Smogorzewski, J. and S.J. Butler (2017). BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities. eLife: e30647DOI:https://doi.org/10.7554/eLife.30647

Clark, Amander

• Pastor, WA., Liu, W., Chen, D., Ho, J., Kim, R., Hunt, T., Lukianchikov, A., Liu, X., Polo, JM., Jacobsen, SE., Clark, AT (2018) TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nature Cell Biology 20, 553-564, https://www.nature.com/articles/s41556-018-0089-0

 

• Gell, JJ., Zhao, J., Chen, D., Hunt, TJ., Clark, AT (2018). PRDM14 is expressed in germ cell tumors with overepression altering human germline differentiation and proliferation. Stem Cell Research 27, 46-56. https://www.sciencedirect.com/science/article/pii/S1873506117302751?via%3Dihub

 

• Tao, Y., Yen, M-R., Chitiashvili, T., Nakano, H., Kim, R., Hosohama, L., Tan, YC, Nakano, A., Chen, P-Y., Clark, AT (2018). Trim28-regulated transposon repression is required for human germline competency and not primed or naive pluripotency. Stem Cell Reports 10(1):243-256, https://www.sciencedirect.com/science/article/pii/S2213671117305283?via%3Dihub

 

• Chen, D., Liu, W., Lukianchikov, A., Hancock, G., Zimmerman, J., Lowe, M., Kim, R., Galic, Z., Irie, N., Surani, MA., Jacobsen, SE., Clark, AT (2017). Germline competency of human embryonic stem cells depends on eomesodermin. Biology of Reproduction 97:850-861 PMC5803789, https://doi.org/10.1093/biolre/iox138

 

• Clark, AT*., Gkountela, G., Chen, D., Liu, W., Sosa, E., Sukhwani, M., Hennebold, JD, Oriwg, KE (2017). Primordial germ cells acquire transplantation potential by Carnegie Stage 23. Stem Cell Reports 9: 329-341 *First and corresponding author. PMC5511048, https://doi.org/10.1016/j.stemcr.2017.05.002

Cohn, Daniel & Krakow, Deborah

• Marques F, Tenney J, Duran I, Martin J, Nevarez L, Pogue R, Krakow D, Cohn DH, Li B. Altered mRNA Splicing, Chondrocyte Gene Expression and Abnormal Skeletal Development due to SF3B4 Mutations in Rodriguez Acrofacial Dysostosis. PLoS Genet 12:e1006307, 2016.

 

• Taylor SP, Bosakova MK, Varecha M, Balek L, Barta T, Trantirek L, Jelinkova I, Duran I, Vesela I, Forlenza KN, Martin JH, Hampl A; University of Washington Center for Mendelian Genomics, Bamshad M, Nickerson D, Jaworski ML, Song J, Ko HW, Cohn DH, Krakow D, Krejci P. An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signaling and causes short rib-polydactyly syndrome. Hum Mol Genet 25:3998-4011, 2016.

 

• Duran I, Taylor SP, Zhang W, Martin J, Forlenza KN, Spiro RP, Nickerson DA, Bamshad M, Cohn DH, Krakow D. Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome. Sci Rep 6:34232, 2016.

 

• Zieba J, Zhang W, Chong JX, Forlenza KN, Martin JH, Heard K, Grange DK, Butler MG, Kleefstra T, Lachman RS, Nickerson D, Regnier M, Cohn DH, Bamshad M, Krakow D. A postnatal role for embryonic myosin revealed by MYH3 mutations that alter TGFβ signaling and cause autosomal dominant spondylocarpotarsal synostosis. Sci Rep 7:41803, 2017.

 

• Duran I, Taylor SP, Zhang W, Martin J, Qureshi F, Jacques SM, Wallerstein R, Lachman RS, Nickerson DA, Bamshad M, Cohn DH, Krakow D. Mutations in IFT-A satellite core component genes IFT43 and IFT121 produce short rib polydactyly syndrome with distinctive campomelia. Cilia 6:7, 2017.

 

• Kunova Bosakova M, Varecha M, Hampl M, Duran I, Nita A, Buchtova M, Dosedelova H, Machat R, Xie Y, Ni Z, Martin JH, Chen L, Jansen G, Krakow D, Krejci P. Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies. Hum Mol Genet 27:1093-1105, 2018.

 

• Csukasi F, Duran I, Barad M, Barta T, Gudernova I, Trantirek L, Martin JH, Kuo CY, Woods J, Lee H, Cohn DH, Krejci P, Krakow D. The PTH/PTHrP-SIK3 pathway affects skeletogenesis through altered mTOR signaling. Sci Transl Med 10(459), 2018.

Coller, Hilary

• Lee HN, Mitra M, Bosompra O, Corney DC, Johnson EL, Rashed N, Ho, LD, Coller HA (2018) RECK isoforms have opposing effects on cell migration.Molecular Biology of the Cell. 29(15):1825-1838. doi: 10.1091/mbc.E17-12-0708. Epub 2018 Jun 6. https://www.molbiolcell.org/doi/abs/10.1091/mbc.E17-12-0708?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

 

• Mithun Mitra; Elizabeth L. Johnson; Vinay S Swamy; Lois Nersesian; David C. Corney; David G. Robinson; Daniel G Taylor; Aaron M. Ambrus; David Jelinek; Wei Wang; Sandra L. Batista; Hilary Coller. (2018) Alternative polyadenylation factors link cell cycle to migration. Genome Biology. GBIO-D-18-00738R2. (Not yet available on-line.)

Crooks, Gay

• Corsell M, Chin CJ, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L, Crooks GM, Peault B. Perivascular support of human hematopoietic stem/progenitor cells. Blood. 2013 Apr 11;121(15):2891-901. PMID: 23412095 PMCID: PMC3707421 http://www.bloodjournal.org/content/121/15/2891?sso-checked=true

 

• Evseenko D, Latour B, Richardson W, Corselli M, Sahaghian A,Cardinal S, Zhu Y, Chan R, Dunn B, Crooks GM.Lysophosphatidic Acid Mediates Myeloid Differentiation within the Human Bone Marrow Microenvironment. PLoS ONE 2013. 8(5): e63718. PMID:23696850 PMCID:PMC3655943 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063718

 

• Chung B, Montel-Hagen A, Ge S, Zhu Y, Parekh C, Blumberg G, Arumugam B, Yang OO, Crooks GM. Engineering the Human Thymic Microenvironment to Support Thymopoiesis in Vivo, Stem Cells 32(9):2386-96, 2014. PMID: 24801626. PMCID: PMC413823. https://stemcellsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/stem.1731

 

• Seet CS, He C, Bethune MT, Li S, Chick B, Gschweng EH, Zhu Y, Kim K, Kohn DB, Baltimore D, *Crooks GM, Montel-Hagen A. Generation of mature T cells from human hematopoietic stem/progenitor cells in artificial thymic organoids, Nature Methods, 2017 May;14(5):521-530. PMC5426913

 

• Seet CS, Crooks GM, Montel-Hagen A. Artificial thymic organoid cultures: In vitro human T-cell differentiation from hematopoietic stem and progenitor cells. Protocol Exchange April 3, 2017. doi:10.1038/protex.2017.062 https://www.nature.com/protocolexchange/protocols/5725

Crosbie-Watson, Rachelle

• Parvatiyar, M.S., Kanashiro-Takeuchi, R.M., Dieseldorff-Jones, K., Brownstein A.J., Collado J.R., Gopal J., Ferrel A., Hammond K.G., Marshall, J.L., Ferrel, A., Beedle, A.M., Chamberlain, J.S., Pinto J.R., and Crosbie-Watson, R.H. “Prevention of early onset cardiac pathology in Duchenne muscular dystrophy models does not require abundant utrophin upregulation.” JCI Insights, in revision.

Deb, Arjun

• Ubil E, Duan J, Pillai I, Rosa-Garrido M, Wu Y, Bargiacchi F, Lu Y, Stanbouly S, Huang J, Rojas M, Vondrinska T, Stefani E & Deb A. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature. 2014; 514: 585-590 [PMID 25317562]. Accompanied by News and Views in Nature. Received Faculty1000 recommendation. www.nature.com/articles/nature13839

 

• Brumm A, Nunez S, Doroudchi M, Kawaguchi R, Duan J, Pellegrini M, Lam L, Carmichael T, Deb A*, Hinman J*. Astrocytes can adopt endothelial cell fates in a p53 dependent manner. Molecular Neurobiology, 2017; 54(6):4584-4596. [PMCID: PMC5219956] *corresponding author/senior author. www.ncbi.nlm.nih.gov/pmc/articles/PMC5219956/

 

• Pillai I, Li S, Romay M, Lam L, Lu Y, Jie Huang, Dillard N, Zemanova M, Rubbi L, Wang Y, Lee J, Xia M, Liang O, Xie Y, Pellegrini M, Lusis A, Deb A. Cardiac fibroblasts adopt osteogenic cell fates and contribute to pathologic heart calcification. Cell Stem Cell, 2017 20(2):218-232 PMID: [27867037]. This paper was featured on the cover of the journal Cell Stem Cell. This paper was also highlighted by Science Magazine as one of the most important/interesting scientific stories. Science 2016. (354): 6318; pg 1389. www.sciencedirect.com/science/article/pii/S1934590916303459?via%3Dihub

 

• Yu J, Seldin M, Fu K, Li S, Lam L, Wang P, Wang Y, Huang D, Nguyen T, Wei B, Kulkarni R, Di Carlo D, Teitell M, Pellegrini M, Lusis AJ & Deb A. Topological arrangement of cardiac fibroblasts regulates cellular plasticity. Circulation Research. 2018; (e-pub) [PMID 29691232] www.ahajournals.org/doi/abs/10.1161/CIRCRESAHA.118.312589?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Geschwind, Daniel

• de la Torre-Ubieta L, Stein JL, Won H, Opland CK, Liang D, Lu D, Geschwind DH. (2018) The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. Cell. 172(1-2):289-304.e18. NIHMSID: NIHMS931857 https://www.sciencedirect.com/science/article/pii/S0092867417314940?via%3Dihub

 

• Damon Polioudakis, Luis de la Torre-Ubieta, Justin Langerman, Andrew G Elkins, Jason L Stein, Celine K Vuong, Carli K Opland, Daning Lu, William Connell, Elizabeth KRuzzo, Jennifer K Lowe, Tarik Hadzic, Flora I Hinz, Shan Sabri, William E Lowry, Kathrin Plath, Daniel H Geschwind. (2018) A single cell transcriptomic analysis of human neocortical development. bioRxiv 401885; doi: https://doi.org/10.1101/401885 https://www.biorxiv.org/content/early/2018/08/28/401885

Gomperts, Brigitte

• Hegab AE, Ha VL, Bisht B, Darmawan DO, Ooi AT, Zhang KX, Paul MK, Kim YS, Gilbert JL, Attiga YS, Alva JA, Nickerson DW, Gomperts BN. Aldehyde dehydrogenase activity enriches for proximal airway epithelial basal stem cells and promotes their proliferation. Stem Cells Dev. 2014 Mar 15;23(6):664-75.
  https://www.liebertpub.com/doi/abs/10.1089/scd.2013.0295?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

 

• Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prev Res (Phila). 2014 May;7(5):487-95. (And Cancer Prevention research cover image May 2014)
  http://cancerpreventionresearch.aacrjournals.org/content/7/5/487.long

 

• Paul MK, Bisht B, Darmawan DO, Chiou R, Ha VL, Wallace WD, Chon AT, Hegab AE, Grogan T, Elashoff DA, Alva-Ornelas JA, Gomperts BN. Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling. Cell Stem Cell. 2014 Aug 7;15(2):199-214. (And Cell Stem Cell Journal cover image for August 2014).
  https://www.sciencedirect.com/science/article/pii/S1934590914001969?via%3Dihub

 

• Sucre J, Wilkinson D, Alva-Ornelas JA, Paul MK, Dunn B, Gomperts BN. A 3-Dimensional Human Model of the Fibroblast Activation that Accompanies Bronchopulmonary Dysplasia Identifies Notch-Mediated Pathophysiology. Am J Physiol Lung Cell Mol Physiol. May 2016. 15;310(10):L889-98. PMID:26968771
  https://www.physiology.org/doi/abs/10.1152/ajplung.00446.2015?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

 

• Wilkinson DC, Alva-Ornelas JA, Sucre JMS, Vijayaraj P, Durra A, Richardson W, Jonas SJ, Paul MK, Karumbayaram S, Dunn B and Gomperts BN. Development of a 3D Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling. Stem Cells Transl 2017 Feb;6(2):622-633. PMID 28191779.
  https://stemcellsjournals.onlinelibrary.wiley.com/doi/abs/10.5966/sctm.2016-0192

 

• Sucre J, Vijayaraj P, Aros CJ, Wilkinson D, Paul MK, Dunn B, Guttentag SH and Gomperts BN. Post-Translational Modification of b-Catenin is Associated with Pathogenic Fibroblastic Changes in Bronchopulmonary Dysplasia. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L186-L195.PMID:27941077 https://www.physiology.org/doi/abs/10.1152/ajplung.00477.2016?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

 

• Hazim RA, Karumbayaram S, Dimashkie A, Jiang M, Lopes VS, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Galic Z, Clark AT, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Differentiation of RPE cells from integration-free iPS cells: cell biological characterization. Stem Cell Res Ther. 2017 Oct 2;8(1):217. PMID: 28969679 https://stemcellres.biomedcentral.com/articles/10.1186/s13287-017-0652-9

 

• Wilkinson DC, Mellody M, Meneses LK, Hope AC, Dunn B and Gomperts BN. Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling. Curr Protoc Stem Cell Biol. 2018 Jun 7:e56. PMID: 29927098 https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpsc.56

Iruela-Arispe, Luisa

• Defalco, T., Saraswathula,A., Briot, A., Iruela-Arispe, M.L., and Capel, B. 2013. Testosterone levels influence mouse fetal leydig cell progenitors through Notch signaling. Biol Reprod. 88(4):91, 1-12. PMCID: PMC4013875. https://academic.oup.com/biolreprod/article/88/4/91,%201-12/2513974

 

• Cristofaro, B., Shi, Y., Faria, M., Suchting, S., Leroyer, A.S., Trindade, A., Duarte, A., Zovein, A.C., Iruela-Arispe, M.L., Nih, L.R., Kubis, N., Henrion, D., Loufrani, L., Todiras, M., Schleifenbaum, J., Gollasch, M., Zhuang, Z.W., Simons, M., Eichmann, A., and le Noble, F. 2013. Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models. Development. 140:1720-1729. PMCID: PMC4074271. http://dev.biologists.org/content/140/8/1720.short

 

• Roodhart, J.M.L., He, H., Daenen, L.G.M., Monvoisin, A., Barber, C., van Amersfoort, M., Hofmann, J.J., Radtke, F., Lane, T.F., Voest, E.E., and Iruela-Arispe, M.L. 2013. Notch1 regulates angio-supportive bone-marrow-derived cells in mice: relevance to chemoresistance. Blood. 122(1):143-153. PMCID: PMC3701902. http://www.bloodjournal.org/content/bloodjournal/122/1/143.full.pdf?sso-checked=true

 

• Janzen, D.M., Rosales, M.A., Paik, D.Y., Lee, D.S., Smith, D.A., Witte, O.N., Iruela-Arispe, M.L., and Memarzadeh, S. 2013. Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy. Cancer Res. 73(15):4697-710. PMCID: PMC3752407. http://cancerres.aacrjournals.org/content/73/15/4697

 

• Goddard, L.M., Ton, A.M., Org, T., Mikkola, H.K., and Iruela-Arispe, M.L. 2013. Selective suppression of endothelial cytokine production by progesterone receptor. Vasc Pharmacol. 59(1-2):36-43. PMCID: PMC3819224. https://www.sciencedirect.com/science/article/pii/S1537189113000748?via%3Dihub

 

• Turlo, K.A., Scapa, J., Bagher, P., Jones, A.W., Feil, R., Korthuis, R.J., Segal, S.S., and Iruela-Arispe, M.L. 2013. b1-Integrin is essential for vasoregulation and smooth muscle survival In Vivo. Arterioscler Thromb Vasc Biol. 33(10):2325-35. PMCID: PMC3882010. https://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.112.300648?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

 

• Corada, M., Orsenigo, F., Morini, M.F., Pitulescu, M. Bhat, G., Nyqvist, D., Breviario, F., Conti, V., Briot, A., Iruela-Arispe, M.L., Adams, R.H., and Dejana, E. 2013. Sox17 is indispensable for acquisition and maintenance of arterial identity. Nat Comm. 4:2609. PMCID: PMC3826640. http://www.nature.com/articles/ncomms3609

 

• Milde, F., Lauw, S., Koumoutsakos, P., and Iruela-Arispe, M.L. 2013. The Mouse Retina in 3D: Quantification of vascular growth and remodeling. Integr Biol (Camb). 5(12):1426-1438.

 

• Warren, C.M., Ziyad, S., Briot, A., Der, A., Iruela-Arispe, M.L. 2014. A Ligand-Independent VEGFR2 Signaling Pathway Limits Angiogenic Responses in Diabetes. Science Signaling. 7(307):ra1. PMCID: PMC4030697. www.ncbi.nlm.nih.gov/pmc/articles/PMC4030697/

 

• Griffin, D.R., Borrajo, J., Soon, A., Acosta-Velez, G.F., Oshita, V., Darling, N., Mack, J., Barker, T., Iruela-Arispe, M.L., and Segura, T. 2014. Hybrid Photopatterned Enzymatic Reaction (HyPER) for in Situ Cell Manipulation. Chembiochem. 15(2):233-242. PMCID: PMC4024472. www.ncbi.nlm.nih.gov/pmc/articles/PMC4024472/

 

• Goddard, L.M., Murphy, J.T., Org, T., Enciso, J.M., Hashimoto-Partyka, M.K., Warren, C.M., Domigan, C.K., McDonald, A.I., He, H., Sanchez, L.A., Allen, N.C., Orsenigo, F., Chao, L.C., Dejana, E., Tontonoz, P., Mikkola, H.K.A., and Iruela-Arispe, M.L. 2014. Progesterone receptor in the vascular endothelium triggers physiological uterine permeability pre-implantation. Cell. 156(3):549-62. PMCID: PMC3985399. https://www.sciencedirect.com/science/article/pii/S0092867413015948?via%3Dihub

 

• Michael, I.P., Westenskow, P., Hacibekiroglu, S., Greenwald, A.C., Ballios, B.G., Kurihara, T., Li, Z., Warren, C.M., Zhang, P., Aguilar, E., Donaldson, L., Marchetti, V., Baba, T., Hussein, S.M., Sung, H., Iruela-Arispe, M.L., Rini, J.M., van der Kooy, D., Friedlander, M., and Nagy, A. 2014. Local acting Sticky-trap inhibits VEGF dependent pathological angiogenesis in the eye. EMBO Mol Med. 6(5):604-23. PMCID: PMC4023884. http://embomolmed.embopress.org/content/6/5/604

 

• Briot, A., Jaroszewicz, A., Warren, C.M., Lu, J., Touma, M., Rudat, C., Hofmann, J.J., Airik R., Weinmaster, G., Lyons, K., Wang, Y., Kispert, A., Pellegrini, M., and Iruela-Arispe, M.L. 2015. Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cell. Dev Cell. 31(6):707-721. PMCID: PMC4311887. https://www.sciencedirect.com/science/article/pii/S1534580714007400?via%3Dihub

 

• Domigan, C.K., Warren, C.M., Antanesian, V., Happel, K., Ziyad, S., Lee, S., Krall, A., Duan, L., Torres-Collado, A.X., Castellani, L.W., Elashoff, D., Christofk, H.R., van der Bliek, A.M., Potente, M., and Iruela-Arispe, M.L. 2015. Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. J Cell Sci. 128(12):2236-2248. PMCID: PMC4487014. http://jcs.biologists.org/content/128/12/2236

 

• Rannou, E., Francois, A., Toullec, A., Guipaud, O., Buard, V., Tarlet, G., Jaillet, C., Iruela-Arispe, M.L., Benderitter, M., Sabourin, J.C., and Milliat, F. 2015. In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury. Sci Rep. 5:15738. PMCID: PMC4625166. http://www.nature.com/articles/srep15738

 

• Moughon, D., He, H., Schokrpur, S., Jiang, Z.K., Jaqoob, M., David, J., Lin, C., Iruela-Arispe, M.L., Dorigo, O., and Wu, L. 2015. Macrophage blockade using CSF1R inhibitors reverses the vascular leakage underlying malignant ascites in late-stage epithelial ovarian cancer. Cancer Res. 75:4742-4752. PMCID: PMC4675660. http://cancerres.aacrjournals.org/content/75/22/4742

 

• Hernandez-Garcia, R., Iruela-Arispe, M.L., Reyes-Cruz, G., and Vazquez-Prado, J. 2015. Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells. Vasc Pharmacol. 74:60-72. https://www.sciencedirect.com/science/article/pii/S1537189115002207?via%3Dihub

 

• Briot, A., Civelek, M., Seki, A., Hoi, K., Mack, J.J., Lee, S.D., Kim, J., Hong, C., Yu, J., Fishbein, G.A., Vakili, L., Fogelman, A.M., Fishbein, M.C., Lusis, A.J., Tontonoz, P., Navab, M., Berliner, J.A., and Iruela-Arispe, M.L. 2015. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. J Exp Med. 212(12):2147-2163. PMCID: PMC4647265. http://jem.rupress.org/content/212/12/2147

 

• Inkeles, M.S., Teles, R.M., Pouldar, D., Andrade, .PR., Madigan, C.A., Lopez, D., Ambrose, M., Noursadeghi, M., Sarno, E.N., Rea, T.H., Ochoa, M.T., Iruela-Arispe, M.L., Swindell, W.R., Ottenhoff, T.H., Geluk, A., Bloom, B.R., Pellegrini, M., and Modlin, R.L. 2016. Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy. JCI Insight. 1(15):e88843. PMCID: PMC5033757. https://insight.jci.org/articles/view/88843

 

• He, H., Mack, J.J., Güç, E., Warren, C.M., Squadrito, M.L., Kilarski., A.A., Baer, C., Freshman, R.D., MacDonald, A.I., Ziyad, S., Swartz, M.A., De Palma, M., and Iruela-Arispe., M.L. 2016. Perivascular macrophages limit permeability. Arterioscl Thromb Vasc Biol. 36:2203-2212. PMCID: PMC5083209. https://www.ahajournals.org/doi/10.1161/ATVBAHA.116.307592

 

• Shirali, A.S., McDonald, A.I., Mack, J.J., and Iruela-Arispe, M.L. 2016. Reproducible arterial denudation injury by infrarenal abdominal aortic clamping in a murine model. J Vis Exp. 117:e54755. https://www.jove.com/video/54755/reproducible-arterial-denudation-injury-infrarenal-abdominal-aortic

 

• Guihard, P.J., Yao, J., Blazquez-Medela, A.M., Iruela-Arispe, L., Bostrom, K.I., and Yao, Y. 2016. Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/ Mice. PLOS One. 11(12):e0167936. PMCID: PMC5148029. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167936

 

• Jumabay, M., Zhumabai, J., Mansurov, N., Niklason, K.C., Guihard, P.J., Fogelman, A.M., Iruela-Arispe, M.L., Yao, Y., Saparov, A., and Bostrom, K.I. 2017. Combined effects of bone morphogenetic protein 10 and crossveinless-2 on cardiomyocyte differentiation in mouse adipocyte-derived stem cells. J Cell Physiol. 233(3):1812-1822. PMCID: PMC5668204. https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.25983

 

• Rose, B.A., Yokota, T., Chintalgattu, V., Ren, S., Iruela-Arispe, M.L., Khakoo, A.Y., and Wang, Y. 2017. Cardiac Myocyte p38α Kinase Regulates Angiogenesis via Myocyte-Endothelial Cell Cross-talk During Stress-Induced Remodeling in Heart. J Biol Chem. 292(31):12787-12800. PMCID: PMC5546022. http://www.jbc.org/content/292/31/12787

 

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• Mundi, S., Massaro, M., Scoditti, E., Carluccio, M.A., van Hunsbergh, V.W.M., Iruela-Arispe, M.L., and De Caterina, R. 2018. Endothelial permeability, LDL deposition, and cardiovascular risk factors-a review. Cardiovasc Res. 114(1): 35-52. https://academic.oup.com/cardiovascres/article/114/1/35/4710347

 

• Ziyad, S., Riordan, J.D., Cavanaugh, A.C., Su, T., Hernandez, G.E., Hilfenhaus, G., Morselli, M., Huynh, K., Wang, K., Chen, J.N., Dupuy, A.J., and Iruela-Arispe, M.L. 2018. A forward genetic screen targeting the endothelium reveals a regulatory role for the lipid kinase Pi4Ka in myelo- and erythropoiesis. Cell Reports. 22(5):1211-1224. PMCID: PMC5828030. https://www.sciencedirect.com/science/article/pii/S2211124718300342?via%3Dihub

 

• Sereti, K.I., Nguyen, N.B., Kamran, P., Zhao, P., Ranjbarvaziri, S., Park, S., Sabri, S., Engel, J.L., Sung, K., Kulkarni, R.P., Ding, Y., Hsiai, T.K., Plath, K., Ernst, J., Sahoo, D., Mikkola, H.K.A., and Iruela-Arispe, M.L., Ardehali, R. 2018. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nat Commun. 9(1): 754. PMCID: PMC5821855. http://www.nature.com/articles/s41467-018-02891-z

 

• Duran, I., Tenney, J., Warren, C.M., Sarukhanov, A., Csukasi, F., Skalansky, M., Iruela-Arispe, M.L., and Krakow, D. 2018. NRP1 haploinsufficiency predisposes to the development of Tetralogy of Fallot. Am J Med Genet A. 176(3): 649-656. https://onlinelibrary.wiley.com/doi/abs/10.1002/ajmg.a.38600

 

• Li, L., Zeng, Q., Bhutkar, A., Galván, J., Karamitopoulou, E., Necsulea, A., Noordermeer, D., Piersigilli, A., Peng, M., Perren, A., Ziobec, I., Robinson, H., Iruela-Arispe, M.L., and Hanahan, D. 2018. GKAP acts as a genetic modulator of NMDAR signaling to govern invasive tumor growth. Cancer Cell. 33(4)736-751.e5. https://www.sciencedirect.com/science/article/pii/S1535610818300643?via%3Dihub

 

• Shirali, A.S., Romay, M.C., McDonald, A.I., Su, T., Steel, M.E., and Iruela-Arispe, M.L. 2018. A multi-step transcriptional cascade underlies vascular regeneration in vivo. Scientific Reports. 8(1):5430. https://www.nature.com/articles/s41598-018-23653-3

 

• Hilfenhaus, G., Nguyen, D., Freshman, J., Prajapati, D., Ma, F., Song, D., Ziyad, S., Cuadrado, M., Pellegrini, M., Bustelo, X.R., and Iruela-Arispe, M.L. 2018. VAV3-induced Cytoskeletal Dynamics Contribute to Heterotypic Properties of Endothelial Barriers. J Cell Biol. https://doi.org/10.1083/jcb.201706041

 

• Chattopadhyay, A., Yang, X., Mukherjee, P., Sulaiman, D., Fogelman, H.R., Grijalva, V., Dubinett, S., Wasler, T.C., Paul, M.K., Salehi-Rad, R., Mack, J.J., Iruela-Arispe, M.L., Navab, M., Fogelman, A.M., and Reddy, S.T. 2018. Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer. Sci Rep. 8(1): 9032. https://www.nature.com/articles/s41598-018-26755-0

 

• Jelinek, D., Flores, A., Uebelhoer, M., Pasque, V., Plath, K., Iruela-Arispe, M.L., Christofk, H.R., Lowry, W.E., and Coller, H.A. 2018. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. J Vis Exp. (136):e58860. https://doi.org/10.3791/57760.

 

• Archer, B., Ueberrueck, T., Mack, J., Yousef, K., Jarenwattananon, N.N., Rall, D., Wypysek, D., Wiese, M., Bluemich, B., Wessling, M., Iruela-Arispe, L., and Bouchard, L. 2018. Non-Invasive Quantification of Cell Density in 3D Gels by MRI. IEEE Trans Biomed Eng. https://doi.org/10.1109/TBME.2018.2857443

 

• McDonald, A.I., Shirali, A.S., Aragón, R., Ma, F., Hernandez, G., Vaughn, D.A., Mack, J.J., Lim, T.Y., Sunshine, H., Zhao, P., Kalinichenko, V., Hai, T., Pelegrini, M., Ardehali, R., and Iruela-Arispe, M.L. 2018. Endothelial Regeneration of Large Vessels is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities. Cell Stem Cell. 23(2):210-225. https://www.sciencedirect.com/science/article/pii/S1934590918303473?via%3Dihub

Jones, Leanne

• J. P. Korzelius, S.K. Naumann, M.A. Loza-Coll, J.S.K.Chan, D. Dutta, J. Oberheim, C. Glaesser, T. Southall, A. Brand, D. L. Jones, B.A. Edgar. 2014. The Snail-family transcription factor escargot maintains stem cell identity and suppresses differentiation in the Drosophila intestine. EMBO Journal. Oct 8. pii: e201489072. [Epub ahead of print] http://emboj.embopress.org/content/33/24/2967.long

 

• M. Loza Coll, T. Southall, S. Sandall, A. Brand, and D.L. Jones. 2014. Regulation of Drosophila intestinal stem cell maintenance and differentiation by the transcription factor Escargot. EMBO Journal. Nov 27. pii: e201489050. [Epub ahead of print]. http://emboj.embopress.org/content/33/24/2983.long

 

• M. Loza-Coll and D. L. Jones. Simultaneous control of stemness and differentiation by the transcription factor Escargot in adult stem cells: how can we tease them apart? 2016. Fly (Austin). Apr 2;10(2):53-9. Epub 2016 Apr 14. PMID: 27077690. https://www.tandfonline.com/doi/full/10.1080/19336934.2016.1176650

 

• Martin Resnik, C. L. Koheler, R. Clarke, J.M. Schinaman, V. Sauer, C. D’Alterio, D. Wong, S. Lewis, Y. Wu, E. Stefani, D. Walker, and D. L. Jones. 2016. Age-related loss of tricellular junction proteins leads to altered stem cell behavior in the Drosophila intestine. Nature Cell Biology. 19 (1): 52-59. doi: 10.1038/ncb3454. Epub 2016 Dec 19. https://www.nature.com/articles/ncb3454

 

• L.P.F. Resende, M. Truong, A. Gomez, and D. L. Jones. Intestinal stem cell ablation reveals differential requirements for survival in response to chemical challenge. 2017. Developmental Biology. Apr 1;424(1):10-17. doi: 10.1016/j.ydbio.2017.01.004. Epub 2017 Jan 17. PMID: 28104389. https://www.sciencedirect.com/science/article/pii/S0012160616302962?via%3Dihub

 

• C. L. Koehler, G. Perkins, Y. Wu, M. Ellisman, D. L. Jones. Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging. Journal of Cell Biology. 2017 Aug 7;216(8):2315-2327. doi:10.1083/jcb.201610036. Epub 2017 Jun 29. PMID:28663346.http://jcb.rupress.org/content/216/8/2315.long

 

• Resnik-Docampo M, Sauer V, Schinaman JM, Clark RI, Walker DW, Jones DL. Keeping it tight: The relationship between bacterial dysbiosis, septate junctions, and the intestinal barrier in Drosophila. Fly (Austin). 2018 Jan 2;12(1):34-40. doi: 10.1080/19336934.2018.1441651. Epub 2018 Mar 6. https://www.ncbi.nlm.nih.gov/pubmed/29455581

Lowry, William

• Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE. Loss of MECP2 leads to activation of P53 and neuronal senescence. Stem Cell Reports. 2018: May08:10(5):1453-1463. https://doi.org/10.1016/j.stemcr.2018.04.001

 

• Germanguz I, Listgarten J, Cinkornpumin J, Solomon A, Gaeta X, Lowry WE. Identifying gene expression modules that define human cell fates. Stem Cell Research. 2016:May: 16(3):712-724. https://doi.org/10.1016/j.scr.2016.04.008

Mikkola, Hanna

• Ueno M, Lee LK, Chhabra A, Kim YJ, Sasidharan R, Van Handel B, Wang Y, Kamata M, Kamran P, Sereti K-J, Ardehali R, Jiang M, Mikkola HKA. c-Met-dependent multipotent labyrinth trophoblast progenitors establish placental exchange interface. Dev Cell 2013;Nov27(4):373-86. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950757/pdf/nihms542056.pdf

 

• Wang W, Org T, Montel-Hagen A, Pioli P, Israely E, Duan D, Malkin D, Flach J, Schiestl R.H, Mikkola HKA. MEF2C Protects Bone Marrow B Lymphoid Progenitors during Stress Hematopoiesis. Nat Commun. 2016 Aug 10;7:12376. doi: 10.1038/ncomms12376. PMID: 27507714 https://www.nature.com/articles/ncomms12376.pdf

 

• Lee LK, Ghorbanian Y, Wang W, Wang Y, Kim YJ, Weissman IL, Inlay MA, Mikkola HKA. LYVE1 marks the divergence of yolk sac definitive hemogenic endothelium from the primitive erythroid lineage. Cell Reports 2016 Nov 22;17(9):2286-2298. doi: 10.1016/j.celrep.2016.10.080. https://www.sciencedirect.com/science/article/pii/S2211124716315157?via%3Dihub

Nakano, Atsushi

• Harmon AW and Nakano A. Nkx2-5 lineage tracing visualizes the distribution of second heart field-derived aortic smooth muscle. Genesis. 2013;51:862-9. https://onlinelibrary.wiley.com/doi/abs/10.1002/dvg.22721

 

• Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnoczky G, Kwon O and Chen JN. Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. Elife. 2015;4. https://elifesciences.org/articles/04801

 

• Nakano H, Minami I, Braas D, Pappoe H, Wu X, Sagadevan A, Vergnes L, Fu K, Morselli M, Dunham C, Ding X, Stieg AZ, Gimzewski JK, Pellegrini M, Clark PM, Reue K, Lusis AJ, Ribalet B, Kurdistani SK, Christofk H, Nakatsuji N and Nakano A. Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. Elife. 2017;6. https://elifesciences.org/articles/29330

Novitch, Bennett

• Sagner A, Gaber ZB, Delile J, Kong JH, Rousso DL, Pearson CA, Weicksel SE, Melchionda M, Mousavy Gharavy SN, Briscoe J, Novitch BG. Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics. PLoS Biol. 2018 Feb 1;16(2):e2003127. doi: 10.1371/journal.pbio.2003127. eCollection 2 18 Feb. PubMed PMID: 29389974; PubMed Central PMCID: PMC5811045. https://www.ncbi.nlm.nih.gov/pubmed/29389974

 

• Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG. Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. Cell Rep. 2017 Oct 10;21(2):517-532. doi: 10.1016/j.celrep.2017.09.047. PubMed PMID: 29020636; PubMed Central PMCID: PMC5637483.https://www.ncbi.nlm.nih.gov/pubmed/29020636

 

• Sangwan S, Zhao A, Adams KL, Jayson CK, Sawaya MR, Guenther EL, Pan AC, Ngo J, Moore DM, Soriaga AB, Do TD, Goldschmidt L, Nelson R, Bowers MT, Koehler CM, Shaw DE, Novitch BG, Eisenberg DS. Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):8770-8775. doi: 10.1073/pnas.1705091114. Epub 2017 Jul 31. PubMed PMID: 28760994; PubMed Central PMCID: PMC5565441.https://www.ncbi.nlm.nih.gov/pubmed/28760994

 

• Varadarajan SG, Kong JH, Phan KD, Kao TJ, Panaitof SC, Cardin J, Eltzschig H, Kania A, Novitch BG, Butler SJ. Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord. Neuron. 2017 May 17;94(4):790-799.e3. doi: 10.1016/j.neuron.2017.03.007. Epub 2017 Apr 21. PubMed PMID: 28434801; PubMed Central PMCID: PMC5576449. https://www.ncbi.nlm.nih.gov/pubmed/28434801

 

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• Kong JH, Yang L, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch BG. Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Dev Cell. 2015 May 26;33(4):373-87. doi:10.1016/j.devcel.2015.03.005. Epub 2015 Apr 30. PubMed PMID: 25936505; PubMed Central PMCID: PMC4449290. https://www.ncbi.nlm.nih.gov/pubmed/25936505

 

• Adams KL, Rousso DL, Umbach JA, Novitch BG. Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015 Apr 14;6:6778. doi: 10.1038/ncomms7778. PubMed PMID: 25868900; PubMed Central PMCID: PMC4397664. https://www.ncbi.nlm.nih.gov/pubmed/25868900

 

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• Gaber ZB, Butler SJ, Novitch BG. PLZF regulates fibroblast growth factor responsiveness and maintenance of neural progenitors. PLoS Biol. 2013 Oct;11(10):e1001676. doi: 10.1371/journal.pbio.1001676. Epub 2013 Oct 8. PubMed PMID: 24115909; PubMed Central PMCID: PMC3792860. https://www.ncbi.nlm.nih.gov/pubmed/24115909

 

• Jacob J, Kong J, Moore S, Milton C, Sasai N, Gonzalez-Quevedo R, Terriente J, Imayoshi I, Kageyama R, Wilkinson DG, Novitch BG, Briscoe J. Retinoid acid specifies neuronal identity through graded expression of Ascl1. Curr Biol. 2013 Mar 4;23(5):412-8. doi: 10.1016/j.cub.2013.01.046. Epub 2013 Feb 14. PubMed PMID: 23416099; PubMed Central PMCID: PMC3659286. https://www.ncbi.nlm.nih.gov/pubmed/23416099Petrigliano, Frank

 

• Bluguermann C, Wu L, Petrigliano FA, McAllister DR, Miriuka S, Evseenko DA.
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• Wu L, Latour B, Gonzalez S, Shah S, Kyupelyan L Galic Z, Van Handel B, Ge S, Zhu Y, Petrigliano FA, Li X, Lyons KM, Crooks GM, McAllister DR, Adams JS, Evseenko D. Human developmental chondrogenesis as a basis for the engineering of chondrocytes from pluripotent stem cells. Stem Cell Reports. 2013 Dec 12;1(6):575-89. PMID:24371811 https://www.sciencedirect.com/science/article/pii/S2213671113001240?via%3Dihub

 

• Leong NL, Arshi A, Kabir N, Nazemi A, Wu BM, Petrigliano FA, McAllister DR. In Vitro and In Vivo Evaluation of Heparin Mediated Growth Factor Delivery from Tissue-Engineered Constructs for Anterior Cruciate Ligament Reconstruction. J Orthop Res. 2015 Feb;33(2):229-36. PMID: 25363620 https://doi.org/10.1002/jor.22757

 

• Petrigliano FA*, Arom GA*, Nazemi AN, Yeranosian MG, Wu B, McAllister DR. In Vivo Evaluation of Electrospun Polycaprolactone Graft for Anterior Cruciate Ligament Engineering. Tissue Eng Part A. 2015 Apr;21(7-8):1228-36.PMID: 25412879 *both authors contributed equally to this work. https://www.liebertpub.com/doi/10.1089/ten.tea.2013.0482

 

• Wu L*, Petrigliano FA*, Ba K, Lee S, Bogdanov J, McAllister DR, Adams JS, Rosenthal AK, Crooks GM, Lin Y, Evseenko DE. Lysophosphadic Acid Mediates Fibrosis In Injured Joints By Regulating Collagen Type I Biosynthesis. Osteoarthritis Cartilage. 2015 Feb;23(2):308-18. PMID: 25464168 *both authors contributed equally to this work. https://doi.org/10.1016/j.joca.2014.11.012

 

• Leong NL, Arshi A, Kabir N, Nazemi A, Wu BM, Petrigliano FA, McAllister DR. Evaluation of Polycaprolactone Scaffold with bFGF and Fibroblasts in an Athymic Rat Model for ACL Reconstruction. Tissue Eng Part A. 2015 Jun;21(11-12):1859-68. PMID: 25744933 https://doi.org/10.1089/ten.tea.2014.0366

 

• Leong NL, Kabir N, Arshi A, Nazemi A, Wu BM, McAllister DR, Petrigliano FA. Athymic Rat Model for Evaluation of Tissue-Engineered Anterior Cruciate Ligament Grafts. J Vis Exp. 2015 Mar 26;(97). PMID: 25867958 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401381/

 

• Choi B, Kim S, Fan J, Kowalski TJ, Petrigliano FA, Evseenko D, Lee M Covalently conjugated transforming growth factor-β1 in modular chitosan hydrogels for the effective treatment of articular cartilage defects. Biomater Sci. 2015 May 21;3(5):742-52. PMID: 26222593 http://pubs.rsc.org/en/Content/ArticleLanding/2015/BM/C4BM00431K#!divAbstract

 

• Zhang S, Ba K, Wu L, Lee S, Peault B, Petrigliano FA, McAllister DR, Adams JS, Evseenko D. Lin Y. Adventitial Cells and Perictyes Support Chondrogenesis Through Different Mechanisms in 3-Dimensional Cultures With or Without Nanoscaffolds. J Biomed Nanotechnol 2015 Oct;11(10):1799-807. PMID: 26502642 https://www.ncbi.nlm.nih.gov/pubmed/26502642

 

• Leong NL, Kabir N, Arshi A, Nazemi A, Jiang J, Wu BM, Petrigliano FA, McAllister DR. Use of ultra-high molecular weight polycaprolactone scaffolds for ACL reconstruction. J Orthop Res 2015 Oct 24. doi: 10.1002/jor.23082. [Epub ahead of print] PMID: 26497133 https://doi.org/10.1002/jor.23082

 

• Kowalski TJ, Leong NL, Wu L, Kabir N, Khan AZ, Pedron A, Karayan A, Lee S, Wu BM, Evseenko D, McAllister DR, Petrigliano FA. Hypoxic Culture Conditions Induce Increased Metabolic Rate and Collagen Gene Expression in ACL-derived Cells. J Orthop Res. 2015 Dec 1. doi: 10.1002/jor.23116. [Epub ahead of print] PMID: 26621359 https://doi.org/10.1002/jor.23116

 

• Markolf KM, Evseenko D, Petrigliano FA. In Vitro Measurement of Joint Stiffness in the Rat Knee. J Biomech Eng. 2016 Feb 10. doi: 10.1115/1.4032693. [Epub ahead of print] PMID: 26863930 http://biomechanical.asmedigitalcollection.asme.org/article.aspx?articleid=2492082

 

• Murray IR, Baily J, Chen WC, Dar A, Gonzalez ZN, Jensen AR, Petrigliano FA, Deb A, Henderson NC. Skeletal and Cardiac Muscle Pericytes: Functions and Therapeutic Potential. Pharmacol Ther. 2016 Sep 2. pii: S0163-7258(16)30161-9. doi: 10.1016/j.pharmthera.2016.09.005. [Epub ahead of print] Review. PMID: 27595928 https://www.researchgate.net/publication/307884322_Skeletal_and_Cardiac_Muscle_Pericytes_Functions_and_Therapeutic_Potential

 

• Eliasberg CD, Dar A, Jensen AR, Murray IR, Hardy WR, Kowalski TJ, Garagozolo CA, Natsuhara KM, Khan AZ, McBride OJ, Cha PI, Kelley BV, Evseenko D, Feeley BT, McAllister DR, Peault B, Petrigliano FA. Perivascular Stem Cells Diminish Muscle Atrophy Following Massive Rotator Cuff Tears in a Small Animal Model. J Bone Joint Surg Am. 2017 Feb 15;99(4):331-341. https://doi.org/10.1177/2325967116S00147

 

• Jensen AR, Kelley BV, Mosich GM, Ariniello A, Eliasberg CD, Vu B, Shah P, Devana SK, Murray IR, Péault B, Dar A, Petrigliano FA. Neer Award 2018: Platelet-derived growth factor receptor α co-expression typifies a subset of platelet-derived growth factor receptor β-positive progenitor cells that contribute to fatty degeneration and fibrosis of the murine rotator cuff. J Shoulder Elbow Surg. 2018 Apr 10. pii: S1058-2746(18)30121-6. doi: 10.1016/j.jse.2018.02.040. [Epub ahead of print] PMID: 29653843 https://doi.org/10.1016/j.jse.2018.02.040

 

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Phelps, Patricia

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Pyle, April

• Haibin Xi, Wakana Fujiwara, Karen Gonzalez, Majib Jan, Simone Liebscher, Ben Van Handel, Katja Schenke-Layland, April D. Pyle. In vivo Human Somitogenesis Guides Somite Development from hPSCs. Cell Reports. 18, 1-13, Feb 7, 2017. https://www.ncbi.nlm.nih.gov/pubmed/28178531

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• Jesse Zaretsky, Angel Garcia Diaz, Daniel Sanghoon Shin, Helena Escuin-Ordinas, Siwen Hu-Lieskovan, Blanca Homet Moreno, Willy Hugo, Davis Y. Torrejon, Gabriel Abril Rodriguez, Salemiz Sandoval, Lucas Barthly, Justin Saco, Riccardo Mezzadra, Bartosz Chmielowski, Katherine Ruchalski, Lidia Robert, Grace Cherry1, Elizabeth Seja, Beata Berent-Maoz1, Begonya Comin-Anduix, Thomas G. Graeber, Paul C. Tumeh, Ton N.M. Schumacher, Roger S. Lo, Antoni Ribas. Mutations associated with acquired resistance to PD-1 blockade in melanoma. New England Journal of Medicine 2016 Sep; 375 (9): 819-29. https://www.nejm.org/doi/10.1056/NEJMoa1604958?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov

 

• Daniel Sanghoon Shin, Jesse M. Zaretsky, Helena Escuin-Ordinas, Angel Garcia-Diaz, Siwen Hu-Lieskovan, Anusha Kalbasi, Catherine S. Grasso, Willy Hugo, Nicolaos Palaskas, Giulia Parisi, Bartosz Chmielowski, Grace Cherry, Elizabeth Seja, Beata Berent-Maoz, I. Peter Shintaku, Dung Thi Lee, Drew M. Pardoll, Luis A. Diaz, Jr, Paul C. Tumeh, Thomas G. Graeber, Roger S. Lo, Begoña Comin-Anduix, Antoni Ribas. Primary resistance to PD-1 blockade mediated by JAK1/2 mutations. Cancer Discovery 2017 Feb; 7 (2): 188-201. http://cancerdiscovery.aacrjournals.org/content/7/2/188.long

 

• Angel Garcia-Diaz, Daniel Sanghoon Shin, Blanca Homet Moreno, Justin Saco, Helena Escuin-Ordinas, Jesse M. Zaretsky, Lu Sun, Willy Hugo, Xiaoyan Wang, Giulia Parisi, Cristina Puig Saus, Thomas G. Graeber, Begonya Comin-Anduix, Robert Damoiseaux, Roger S. Lo, Antoni Ribas. Interferon signaling pathway regulating PD-L1 and PD-L2 expression. Cell Reports 2017 May 9; 19 (6): 1189-1201. https://www.cell.com/cell-reports/pdf/S2211-1247(17)30525-9.pdf

Sofroniew, Michael

• Anderson MA, Burda JE, Ren Y, Ao Y, O’Shea TM, Kawaguchi R, Coppola G, Khakh BS, Deming TJ, Sofroniew MV (2016) Astrocyte scar formation aids central nervous system axon regeneration. Nature 532:195-200. https://www.nature.com/articles/nature17623

 

• Anderson MA, O’Shea TM, Burda JE, Ao Y, Barlatey SL, Bernstein AM, Kim JH, James ND, Rogers A, Kato B, Wollenberg AL, Kawaguchi R, Coppola G, Wang C, Deming TJ, He Z, Courtine G, Sofroniew MV (2018) Required growth facilitators propel axon regeneration across complete spinal cord injury. Nature 561:396-400. https://www.nature.com/articles/s41586-018-0467-6

 

• Ren Y, Ao Y, O’Shea TM, Burda JE, Bernstein AM, Brumm AJ, Muthusamy N, Ghashghaei HT, Carmichael ST, Cheng L, Sofroniew MV (2017) Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury. Sci Rep 7:41122.https://www.nature.com/articles/srep41122

 

• Wanner IB, Anderson MA, Song B, Levine J, Fernandez A, Gray-Thompson Z, Ao Y, Sofroniew MV (2013) Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury. J Neurosci 33:12870-12886. http://www.jneurosci.org/content/33/31/12870

 

• Wollenberg AL, O’Shea TM, Kim JH, Czechanski A, Reinholdt LG, Sofroniew MV, Deming TJ (2018) Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery. Biomaterials 178:527-545. https://www.ncbi.nlm.nih.gov/pubmed/29657091

 

• Zhang S, Burda JE, Anderson MA, Zhao Z, Ao Y, Cheng Y, Sun Y, Deming TJ, Sofroniew MV (2015b) Thermoresponsive Copolypeptide Hydrogel Vehicles for Central Nervous System Cell Delivery. ACS Biomater Sci Eng 1:705-717. https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.5b00153

 

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Witte, Owen

• Lee JK, Bangayan NJ, Chai T, Smith BA, Pariva TE, Yun S, Vashisht A, Zhang Q, Park JW, Corey E, Huang J, Graeber TG, Wohlschlegel J, Witte ON. (2018) Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of prostate cancer. Proc Natl Acad Sci. 115(19). E4473-E4482. http://www.pnas.org/content/early/2018/04/19/1802354115.short

 

• Bethune MT, Li X-H, Yu J, McLaughlin J, Cheng D, Mathis C, Morena BH, Woods K, Knights, AJ, Garcia-Diaz A, Wong S, Hu-Lieskovan S, Puig-Saus C, Cebon J, Ribas A, Yang L, Witte ON, Baltimore D. 2018. Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various major histocompatibility complex molecules. Proc Natl Acad Sci. In Press.