George Agak
Publications:
Sennett ML, Agak GW, Thiboutot DM, Nelson AM. Transcriptomic Analyses Predict Enhanced Metabolic Activity and Therapeutic Potential of mTOR Inhibitors in Acne-Prone Skin. JID Innov. 2024 Nov; 4(6):100306. view on PubMed
Deng M, Odhiambo WO, Qin M, To TT, Brewer GM, Kheshvadjian AR, Cheng C, Agak GW. Analysis of intracellular communication reveals consistent gene changes associated with early-stage acne skin. Cell Commun Signal. 2024 Aug 14; 22(1):400. view on PubMed
Deng M, Odhiambo WO, Qin M, To TT, Brewer GM, Kheshvadjian AR, Cheng C, Agak GW. Analysis of Intracellular Communication Reveals Consistent Gene Changes Associated with Early-Stage Acne Skin. Res Sq. 2024 May 29. view on PubMed
To TT, Oparaugo NC, Kheshvadjian AR, Nelson AM, Agak GW. Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection. Int J Mol Sci. 2024 Feb 07; 25(4). view on PubMed
Agak GW, Thiboutot DM, Zaenglein AL, Nelson AM. SLST D1 strains may contribute to skin health. Exp Dermatol. 2024 Jan; 33(1):e14968. view on PubMed
Nolan ZT, Banerjee K, Cong Z, Gettle SL, Longenecker AL, Kawasawa YI, Zaenglein AL, Thiboutot DM, Agak GW, Zhan X, Nelson AM. Treatment response to isotretinoin correlates with specific shifts in Cutibacterium acnes strain composition within the follicular microbiome. Exp Dermatol. 2023 07; 32(7):955-964. view on PubMed
Oparaugo NC, Ouyang K, Nguyen NPN, Nelson AM, Agak GW. Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers. Int J Mol Sci. 2023 Jan 12; 24(2). view on PubMed
Konate D, Diawara SI, Sogoba N, Shaffer J, Keita B, Cisse A, Sanogo I, Dicko I, Guindo MDA, Balam S, Traore A, Kante S, Dembele A, Kasse F, Denou L, Diakite SAS, Traore K, M'Baye Thiam S, Sanogo V, Toure M, Diarra A, Agak GW, Doumbia S, Diakite M. Effect of a fifth round of seasonal malaria chemoprevention in children aged 5-14 years in Dangassa, an area of long transmission in Mali. Parasite Epidemiol Control. 2023 Feb; 20:e00283. view on PubMed
Nguyen NPN, Oparaugo NC, Ouyang K, Agak GW. A protocol to detect human CD4+ T cell extracellular traps using scanning electron microscopy. STAR Protoc. 2023 03 17; 4(1):101932. view on PubMed
Nang'ole WF, Omu A, Ogeng'o JA, Agak GW. Do Mesenchymal Stem Cells Influence Keloid Recurrence? Stem Cells Cloning. 2022; 15:77-84. view on PubMed
Ouyang K, Zheng DX, Agak GW. T-Cell Mediated Immunity in Merkel Cell Carcinoma. Cancers (Basel). 2022 Dec 09; 14(24). view on PubMed
Schneider AM, Nolan ZT, Banerjee K, Paine AR, Cong Z, Gettle SL, Longenecker AL, Zhan X, Agak GW, Nelson AM. Evolution of the facial skin microbiome during puberty in normal and acne skin. J Eur Acad Dermatol Venereol. 2023 Jan; 37(1):166-175. view on PubMed
Ouyang K, Oparaugo N, Nelson AM, Agak GW. T Cell Extracellular Traps: Tipping the Balance Between Skin Health and Disease. Front Immunol. 2022; 13:900634. view on PubMed
Nangole FW, Agak G. The effects of negative pressure wound therapy on wounds with cerebrospinal fluid leakages. J Wound Care. 2022 Apr 02; 31(4):348-351. view on PubMed
Wanjala NF, Joseph G, Anthony M, Primus O, Ogeng'o JJ, Anzala O, Dohil I, Agak GW. Keloids: Does patients' sex influence the presentation and recurrence post-excision? J Plast Reconstr Aesthet Surg. 2022 Jan; 75(1):366-368. view on PubMed
Nangole FW, Ouyang K, Anzala O, Ogeng'o J, Agak GW, Zuriel D. Does Keloid Histology Influence Recurrence? Am J Dermatopathol. 2021 Sep 01; 43(9):642-646. view on PubMed
Nangole FW, Ouyang K, Anzala O, Ogengo J, Agak GW. Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease? J Inflamm Res. 2021; 14:2465-2470. view on PubMed
Agak GW, Mouton A, Teles RM, Weston T, Morselli M, Andrade PR, Pellegrini M, Modlin RL. Extracellular traps released by antimicrobial TH17 cells contribute to host defense. J Clin Invest. 2021 01 19; 131(2). view on PubMed
Nangole FW, Agak GW. Keloid pathophysiology: fibroblast or inflammatory disorders? JPRAS Open. 2019 Dec; 22:44-54. view on PubMed
Park AJ, Agak GW, Qin M, Hisaw LD, Pirouz A, Kao S, Marinelli LJ, Garbán HJ, Thiboutot D, Liu PT, Kim J. G2A Attenuates Propionibacterium acnes Induction of Inflammatory Cytokines in Human Monocytes. Ann Dermatol. 2017 Dec; 29(6):688-698. view on PubMed
Agak GW, Kao S, Ouyang K, Qin M, Moon D, Butt A, Kim J. Phenotype and Antimicrobial Activity of Th17 Cells Induced by Propionibacterium acnes Strains Associated with Healthy and Acne Skin. J Invest Dermatol. 2018 02; 138(2):316-324. view on PubMed
Yu Y, Champer J, Agak GW, Kao S, Modlin RL, Kim J. Different Propionibacterium acnes Phylotypes Induce Distinct Immune Responses and Express Unique Surface and Secreted Proteomes. J Invest Dermatol. 2016 11; 136(11):2221-2228. view on PubMed
Hisaw LD, Qin M, Park A, Agak GW, Pirouz A, Phan J, Fernandez C, Garbán HJ, Nelson A, Thiboutot D, Kim J. Antimicrobial Activity of Sebocytes against Propionibacterium acnes via Toll-Like Receptor 2 and Lysosomal Pathway. J Invest Dermatol. 2016 10; 136(10):2098-2101. view on PubMed
Qin M, Landriscina A, Rosen JM, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler BL, Krausz AE, Friedman JM, Nosanchuk JD, Kim J, Friedman AJ. Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response. J Invest Dermatol. 2015 Nov; 135(11):2723-2731. view on PubMed
Schmidt NW, Agak GW, Deshayes S, Yu Y, Blacker A, Champer J, Xian W, Kasko AM, Kim J, Wong GCL. Pentobra: A Potent Antibiotic with Multiple Layers of Selective Antimicrobial Mechanisms against Propionibacterium Acnes. J Invest Dermatol. 2015 Jun; 135(6):1581-1589. view on PubMed
Agak GW, Qin M, Nobe J, Kim MH, Krutzik SR, Tristan GR, Elashoff D, Garbán HJ, Kim J. Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D. J Invest Dermatol. 2014 Feb; 134(2):366-373. view on PubMed
Olugbile S, Villard V, Bertholet S, Jafarshad A, Kulangara C, Roussilhon C, Frank G, Agak GW, Felger I, Nebie I, Konate K, Kajava AV, Schuck P, Druilhe P, Spertini F, Corradin G. Malaria vaccine candidate: design of a multivalent subunit α-helical coiled coil poly-epitope. Vaccine. 2011 Sep 16; 29(40):7090-9. view on PubMed
Agak GW, Bejon P, Fegan G, Gicheru N, Villard V, Kajava AV, Marsh K, Corradin G. Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya. Vaccine. 2008 Apr 07; 26(16):1963-71. view on PubMed
Villard V, Agak GW, Frank G, Jafarshad A, Servis C, Nébié I, Sirima SB, Felger I, Arevalo-Herrera M, Herrera S, Heitz F, Bäcker V, Druilhe P, Kajava AV, Corradin G. Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif. PLoS One. 2007 Jul 25; 2(7):e645. view on PubMed
