Joseph Crompton
Publications:
Al Shihabi A, Tebon PJ, Nguyen HTL, Chantharasamee J, Sartini S, Davarifar A, Jensen AY, Diaz-Infante M, Cox H, Gonzalez AE, Norris S, Sperry J, Nakashima J, Tavanaie N, Winata H, Fitz-Gibbon ST, Yamaguchi TN, Jeong JH, Dry S, Singh AS, Chmielowski B, Crompton JG, Kalbasi AK, Eilber FC, Hornicek F, Bernthal NM, Nelson SD, Boutros PC, Federman NC, Yanagawa J, Soragni A. The landscape of drug sensitivity and resistance in sarcoma. Cell Stem Cell. 2024 Oct 03; 31(10):1524-1542.e4. view on PubMed
Klingbeil KD, Wilde BR, Graham DS, Lofftus S, McCaw T, Matulionis N, Dry SM, Crompton JG, Eilber FC, Graeber TG, Shackelford DB, Christofk HR, Kadera BE. Targeting Asparagine Metabolism in Well-Differentiated/Dedifferentiated Liposarcoma. Cancers (Basel). 2024 Aug 30; 16(17). view on PubMed
Shehata MS, Lofftus SY, Park JY, Singh AS, Federman NC, Eilber FC, Crompton JG, McCaw TR. Sarcoma in patients with Lynch syndrome and response to immunotherapy. J Surg Oncol. 2024 Mar; 129(4):820-826. view on PubMed
McCaw TR, Lofftus SY, Crompton JG. Clonal redemption of B cells in cancer. Front Immunol. 2023; 14:1277597. view on PubMed
Klingbeil KD, Tang JP, Graham DS, Lofftus SY, Jaiswal AK, Lin TL, Frias C, Chen LY, Nakasaki M, Dry SM, Crompton JG, Eilber FC, Rao DS, Kalbasi A, Kadera BE. IGF2BP3 as a Prognostic Biomarker in Well-Differentiated/Dedifferentiated Liposarcoma. Cancers (Basel). 2023 Sep 09; 15(18). view on PubMed
Al Shihabi A, Tebon PJ, Nguyen HTL, Chantharasamee J, Sartini S, Davarifar A, Jensen AY, Diaz-Infante M, Cox H, Gonzalez AE, Swearingen S, Tavanaie N, Dry S, Singh A, Chmielowski B, Crompton JG, Kalbasi A, Eilber FC, Hornicek F, Bernthal N, Nelson SD, Boutros PC, Federman N, Yanagawa J, Soragni A. The landscape of drug sensitivity and resistance in sarcoma. bioRxiv. 2023 Aug 08. view on PubMed
Crane JN, Graham DS, Mona CE, Nelson SD, Samiei A, Dawson DW, Dry SM, Masri MG, Crompton JG, Benz MR, Czernin J, Eilber FC, Graeber TG, Calais J, Federman NC. Fibroblast Activation Protein Expression in Sarcomas. Sarcoma. 2023; 2023:2480493. view on PubMed
Hotta M, Mona CE, Crompton JG, Armstrong WR, Gafita A, Nelson SD, Eilber FC, Dawson DW, Calais J, Benz MR. FAPI PET Signal in Hibernoma Reflects FAP Expression in Tumor Vasculature Cells. Clin Nucl Med. 2023 Jul 01; 48(7):e353-e355. view on PubMed
Patel SP, Othus M, Chen Y, Wright GP, Yost KJ, Hyngstrom JR, Hu-Lieskovan S, Lao CD, Fecher LA, Truong TG, Eisenstein JL, Chandra S, Sosman JA, Kendra KL, Wu RC, Devoe CE, Deutsch GB, Hegde A, Khalil M, Mangla A, Reese AM, Ross MI, Poklepovic AS, Phan GQ, Onitilo AA, Yasar DG, Powers BC, Doolittle GC, In GK, Kokot N, Gibney GT, Atkins MB, Shaheen M, Warneke JA, Ikeguchi A, Najera JE, Chmielowski B, Crompton JG, Floyd JD, Hsueh E, Margolin KA, Chow WA, Grossmann KF, Dietrich E, Prieto VG, Lowe MC, Buchbinder EI, Kirkwood JM, Korde L, Moon J, Sharon E, Sondak VK, Ribas A. Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma. N Engl J Med. 2023 Mar 02; 388(9):813-823. view on PubMed
Kendal JK, Shehata MS, Lofftus SY, Crompton JG. Cancer-Associated B Cells in Sarcoma. Cancers (Basel). 2023 Jan 19; 15(3). view on PubMed
Eckardt MA, Graham DS, Klingbeil KD, Lofftus SY, McCaw TR, Bailey MJ, Goldring CJ, Kendal JK, Kadera BE, Nelson SD, Dry SM, Kalbasi AK, Singh AS, Chmielowski B, Eilber FR, Eilber FC, Crompton JG. Lifelong Imaging Surveillance is Indicated for Patients with Primary Retroperitoneal Liposarcoma. Ann Surg Oncol. 2023 May; 30(5):3097-3103. view on PubMed
Crompton JG, Armstrong WR, Eckardt MA, Seyedroudbari A, Tap WD, Dry SM, Abt ER, Calais J, Herrmann K, Czernin J, Eilber FC, Benz MR. 18F-FLT PET/CT as a Prognostic Imaging Biomarker of Disease-Specific Survival in Patients with Primary Soft-Tissue Sarcoma. J Nucl Med. 2022 05; 63(5):708-712. view on PubMed
Hotta M, Benz MR, Allen-Auerbach MS, Crompton JG, Roth MD, Eilber FC, Calais J. High 68 Ga-FAPI-46 uptake in a pulmonary necrotizing granuloma in a patient with subcutaneous lipoma. Eur J Nucl Med Mol Imaging. 2022 02; 49(3):1088-1089. view on PubMed
Benz MR, Crompton JG, Harder D. PET/CT Variants and Pitfalls in Bone and Soft Tissue Sarcoma. Semin Nucl Med. 2021 11; 51(6):584-592. view on PubMed
Crompton JG, Busam KJ, Bartlett EK. Interpretation of the Complex Melanoma Pathology Report. Surg Oncol Clin N Am. 2020 Jul; 29(3):327-338. view on PubMed
Osorio JC, Arbour KC, Le DT, Durham JN, Plodkowski AJ, Halpenny DF, Ginsberg MS, Sawan P, Crompton JG, Yu HA, Namakydoust A, Nabet BY, Chaft JE, Riely GJ, Rizvi H, Diaz LA, Hellmann MD. Lesion-Level Response Dynamics to Programmed Cell Death Protein (PD-1) Blockade. J Clin Oncol. 2019 12 20; 37(36):3546-3555. view on PubMed
Crompton JG, Crompton PD, Matzinger P. Does Atelectasis Cause Fever After Surgery? Putting a Damper on Dogma. JAMA Surg. 2019 05 01; 154(5):375-376. view on PubMed
Crompton JG, Gilbert E, Brady MS. Clinical implications of the eighth edition of the American Joint Committee on Cancer melanoma staging. J Surg Oncol. 2019 Jan; 119(2):168-174. view on PubMed
Crompton JG, Klemen ND, Kammula US. Correction to: Metastasectomy for Tumor-Infiltrating Lymphocytes: An Emerging Operative Indication in Surgical Oncology. Ann Surg Oncol. 2018 12; 25(Suppl 3):986. view on PubMed
Crompton JG, Jimenez JM, Chen F, Hines OJ. Man with liver abscess and pneumobilia. Surgery. 2018 04; 163(4):965-966. view on PubMed
Crompton JG, Ogura K, Bernthal NM, Kawai A, Eilber FC. Local Control of Soft Tissue and Bone Sarcomas. J Clin Oncol. 2018 01 10; 36(2):111-117. view on PubMed
Klebanoff CA, Crompton JG, Leonardi AJ, Yamamoto TN, Chandran SS, Eil RL, Sukumar M, Vodnala SK, Hu J, Ji Y, Clever D, Black MA, Gurusamy D, Kruhlak MJ, Jin P, Stroncek DF, Gattinoni L, Feldman SA, Restifo NP. Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy. JCI Insight. 2017 12 07; 2(23). view on PubMed
Crompton JG, Klemen N, Kammula US. Metastasectomy for Tumor-Infiltrating Lymphocytes: An Emerging Operative Indication in Surgical Oncology. Ann Surg Oncol. 2018 Feb; 25(2):565-572. view on PubMed
Russell TA, Eckardt MA, Murakami T, Elliott IA, Kawaguchi K, Kiyuna T, Igarashi K, Li Y, Crompton JG, Graham DS, Dry SM, Bernthal N, Yanagawa J, Kalbasi A, Federman N, Chmielowski B, Singh AS, Hoffman RM, Eilber FC. Clinical Factors That Affect the Establishment of Soft Tissue Sarcoma Patient-Derived Orthotopic Xenografts: A University of California, Los Angeles, Sarcoma Program Prospective Clinical Trial. JCO Precis Oncol. 2017; 2017. view on PubMed
Shurell E, Vergara-Lluri ME, Li Y, Crompton JG, Singh A, Bernthal N, Wu H, Eilber FC, Dry SM. Comprehensive adipocytic and neurogenic tissue microarray analysis of NY-ESO-1 expression - a promising immunotherapy target in malignant peripheral nerve sheath tumor and liposarcoma. Oncotarget. 2016 Nov 08; 7(45):72860-72867. view on PubMed
Shurell E, Singh AS, Crompton JG, Jensen S, Li Y, Dry S, Nelson S, Chmielowski B, Bernthal N, Federman N, Tumeh P, Eilber FC. Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. Oncotarget. 2016 Sep 27; 7(39):64300-64308. view on PubMed
Crompton JG, Dawes AJ, Donald GW, Livhits MJ, Chandler CF. Perineural bupivacaine injection reduces inguinodynia after inguinal hernia repair. Surgery. 2016 12; 160(6):1528-1532. view on PubMed
Kiyuna T, Murakami T, Tome Y, Igarashi K, Kawaguchi K, Russell T, Eckardt MA, Crompton J, Singh A, Bernthal N, Bukata S, Federman N, Kanaya F, Eilber FC, Hoffman RM. Labeling the Stroma of a Patient-Derived Orthotopic Xenograft (PDOX) Mouse Model of Undifferentiated Pleomorphic Soft-Tissue Sarcoma With Red Fluorescent Protein for Rapid Non-Invasive Imaging for Drug Screening. J Cell Biochem. 2017 02; 118(2):361-365. view on PubMed
Roychoudhuri R, Eil RL, Clever D, Klebanoff CA, Sukumar M, Grant FM, Yu Z, Mehta G, Liu H, Jin P, Ji Y, Palmer DC, Pan JH, Chichura A, Crompton JG, Patel SJ, Stroncek D, Wang E, Marincola FM, Okkenhaug K, Gattinoni L, Restifo NP. The transcription factor BACH2 promotes tumor immunosuppression. J Clin Invest. 2016 Feb; 126(2):599-604. view on PubMed
Crompton JG, Sukumar M, Restifo NP. Targeting Akt in cell transfer immunotherapy for cancer. Oncoimmunology. 2016; 5(9):e1014776. view on PubMed
Klebanoff CA, Scott CD, Leonardi AJ, Yamamoto TN, Cruz AC, Ouyang C, Ramaswamy M, Roychoudhuri R, Ji Y, Eil RL, Sukumar M, Crompton JG, Palmer DC, Borman ZA, Clever D, Thomas SK, Patel S, Yu Z, Muranski P, Liu H, Wang E, Marincola FM, Gros A, Gattinoni L, Rosenberg SA, Siegel RM, Restifo NP. Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy. J Clin Invest. 2016 Jan; 126(1):318-34. view on PubMed
Sukumar M, Liu J, Mehta GU, Patel SJ, Roychoudhuri R, Crompton JG, Klebanoff CA, Ji Y, Li P, Yu Z, Whitehill GD, Clever D, Eil RL, Palmer DC, Mitra S, Rao M, Keyvanfar K, Schrump DS, Wang E, Marincola FM, Gattinoni L, Leonard WJ, Muranski P, Finkel T, Restifo NP. Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy. Cell Metab. 2016 Jan 12; 23(1):63-76. view on PubMed
Palmer DC, Guittard GC, Franco Z, Crompton JG, Eil RL, Patel SJ, Ji Y, Van Panhuys N, Klebanoff CA, Sukumar M, Clever D, Chichura A, Roychoudhuri R, Varma R, Wang E, Gattinoni L, Marincola FM, Balagopalan L, Samelson LE, Restifo NP. Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance. J Exp Med. 2015 Nov 16; 212(12):2095-113. view on PubMed
Tufaro AP, Azoury SC, Crompton JG, Straughan DM, Reddy S, Prasad NB, Shi G, Fischer AC. Rising incidence and aggressive nature of cutaneous malignancies after transplantation: An update on epidemiology, risk factors, management and surveillance. Surg Oncol. 2015 Dec; 24(4):345-52. view on PubMed
Crompton JG, Narayanan M, Cuddapah S, Roychoudhuri R, Ji Y, Yang W, Patel SJ, Sukumar M, Palmer DC, Peng W, Wang E, Marincola FM, Klebanoff CA, Zhao K, Tsang JS, Gattinoni L, Restifo NP. Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape. Cell Mol Immunol. 2016 07; 13(4):502-13. view on PubMed
Azoury SC, Crompton JG, Straughan DM, Klemen ND, Reardon ES, Beresnev TH, Hughes MS. Unknown primary nasopharyngeal melanoma presenting as severe recurrent epistaxis and hearing loss following treatment and remission of metastatic disease: A case report and literature review. Int J Surg Case Rep. 2015; 10:232-5. view on PubMed
Crompton JG, Sukumar M, Roychoudhuri R, Clever D, Gros A, Eil RL, Tran E, Hanada K, Yu Z, Palmer DC, Kerkar SP, Michalek RD, Upham T, Leonardi A, Acquavella N, Wang E, Marincola FM, Gattinoni L, Muranski P, Sundrud MS, Klebanoff CA, Rosenberg SA, Fearon DT, Restifo NP. Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics. Cancer Res. 2015 Jan 15; 75(2):296-305. view on PubMed
Acquavella N, Clever D, Yu Z, Roelke-Parker M, Palmer DC, Xi L, Pflicke H, Ji Y, Gros A, Hanada K, Goldlust IS, Mehta GU, Klebanoff CA, Crompton JG, Sukumar M, Morrow JJ, Franco Z, Gattinoni L, Liu H, Wang E, Marincola F, Stroncek DF, Lee CC, Raffeld M, Bosenberg MW, Roychoudhuri R, Restifo NP. Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest. Cancer Immunol Res. 2015 Jan; 3(1):37-47. view on PubMed
Crompton JG, Nacev BA, Upham T, Azoury SC, Eil R, Cameron DE, Haider AH. Traumatic ventricular septal defect resulting in severe pulmonary hypertension. J Surg Case Rep. 2014 Oct 18; 2014(10). view on PubMed
Crompton JG, Clever D, Vizcardo R, Rao M, Restifo NP. Reprogramming antitumor immunity. Trends Immunol. 2014 Apr; 35(4):178-85. view on PubMed
Crompton JG, Sukumar M, Restifo NP. Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy. Immunol Rev. 2014 Jan; 257(1):264-276. view on PubMed
Crompton JG, Oyetunji TA, Haut ER, Cornwell EE, Haider AH. Systematically Tabulated Outcomes Research Matrix (STORM): a methodology to generate research hypotheses. Surgery. 2014 Mar; 155(3):541-4. view on PubMed
Sukumar M, Liu J, Ji Y, Subramanian M, Crompton JG, Yu Z, Roychoudhuri R, Palmer DC, Muranski P, Karoly ED, Mohney RP, Klebanoff CA, Lal A, Finkel T, Restifo NP, Gattinoni L. Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function. J Clin Invest. 2013 Oct; 123(10):4479-88. view on PubMed
Roychoudhuri R, Hirahara K, Mousavi K, Clever D, Klebanoff CA, Bonelli M, Sciumè G, Zare H, Vahedi G, Dema B, Yu Z, Liu H, Takahashi H, Rao M, Muranski P, Crompton JG, Punkosdy G, Bedognetti D, Wang E, Hoffmann V, Rivera J, Marincola FM, Nakamura A, Sartorelli V, Kanno Y, Gattinoni L, Muto A, Igarashi K, O'Shea JJ, Restifo NP. BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Nature. 2013 Jun 27; 498(7455):506-10. view on PubMed
Kerkar SP, Leonardi AJ, van Panhuys N, Zhang L, Yu Z, Crompton JG, Pan JH, Palmer DC, Morgan RA, Rosenberg SA, Restifo NP. Collapse of the tumor stroma is triggered by IL-12 induction of Fas. Mol Ther. 2013 Jul; 21(7):1369-77. view on PubMed
Crompton JG, Rao M, Restifo NP. Memoirs of a reincarnated T cell. Cell Stem Cell. 2013 Jan 03; 12(1):6-8. view on PubMed
Crompton JG, Oyetunji TA, Pollack KM, Stevens K, Cornwell EE, Efron DT, Haut ER, Haider AH. Association between helmets and facial injury after a motorcycle collision: an analysis of more than 40 000 patients from the National Trauma Data Bank. Arch Surg. 2012 Jul; 147(7):674-6. view on PubMed
Haider AH, Crompton JG, Oyetunji T, Risucci D, DiRusso S, Basdag H, Villegas CV, Syed ZU, Haut ER, Efron DT. Mechanism of injury predicts case fatality and functional outcomes in pediatric trauma patients: the case for its use in trauma outcomes studies. J Pediatr Surg. 2011 Aug; 46(8):1557-63. view on PubMed
Oyetunji TA, Chang DC, Crompton JG, Greene WR, Efron DT, Haut ER, Cornwell EE, Haider AH. Redefining hypotension in the elderly: normotension is not reassuring. Arch Surg. 2011 Jul; 146(7):865-9. view on PubMed
Crompton JG, Bone C, Oyetunji T, Pollack KM, Bolorunduro O, Villegas C, Stevens K, Cornwell EE, Efron DT, Haut ER, Haider AH. Motorcycle helmets associated with lower risk of cervical spine injury: debunking the myth. J Am Coll Surg. 2011 Mar; 212(3):295-300. view on PubMed
Oyetunji TA, Crompton JG, Ehanire ID, Stevens KA, Efron DT, Haut ER, Chang DC, Cornwell EE, Crandall ML, Haider AH. Multiple imputation in trauma disparity research. J Surg Res. 2011 Jan; 165(1):e37-41. view on PubMed
Haider AH, Crompton JG, Chang DC, Efron DT, Haut ER, Handly N, Cornwell EE. Evidence of hormonal basis for improved survival among females with trauma-associated shock: an analysis of the National Trauma Data Bank. J Trauma. 2010 Sep; 69(3):537-40. view on PubMed
Crompton J, Kingham TP, Kamara TB, Brennan MF, Kushner AL. Comparison of surgical care deficiencies between US civil war hospitals and present-day hospitals in Sierra Leone. World J Surg. 2010 Aug; 34(8):1743-7. view on PubMed
Crompton JG, Pollack KM, Oyetunji T, Chang DC, Efron DT, Haut ER, Cornwell EE, Haider AH. Racial disparities in motorcycle-related mortality: an analysis of the National Trauma Data Bank. Am J Surg. 2010 Aug; 200(2):191-6. view on PubMed
Crompton JG, Oyetunji T, Stevens KA, Efron DT, Haut ER, Haider AH. Motorcycle helmets save lives, but not limbs: a National Trauma Data Bank analysis of functional outcomes after motorcycle crash. J Surg Res. 2010 Jan; 158(1):1-5. view on PubMed
Oyetunji T, Crompton JG, Efron DT, Haut ER, Chang DC, Cornwell EE, Baker SP, Haider AH. Simplifying physiologic injury severity measurement for predicting trauma outcomes. J Surg Res. 2010 Apr; 159(2):627-32. view on PubMed
Haider AH, Crompton JG, Oyetunji T, Stevens KA, Efron DT, Kieninger AN, Chang DC, Cornwell EE, Haut ER. Females have fewer complications and lower mortality following trauma than similarly injured males: a risk adjusted analysis of adults in the National Trauma Data Bank. Surgery. 2009 Aug; 146(2):308-15. view on PubMed
Cahill B, Crompton J, Somerville T, O'rourke M, Parker S, Stringham J, Karwande S. Early experience with sirolimus in lung transplant recipients. J Heart Lung Transplant. 2001 Feb; 20(2):162. view on PubMed
